Lanozole 15 mg (Capsule (Enteric Coated))

Unit Price: ৳ 3.00 (40's pack: ৳ 120.00)

Medicine Details

Category Details
Generic Lansoprazole
Company Medimet pharmaceuticals ltd
Also available as
Lanozole 30 mg capsule

Title

Lanozole

Categories

  • Medicine
  • Pharmaceutical

Description

Lanozole is a proton pump inhibitor indicated for the short term treatment of active duodenal ulcer, maintenance of healed duodenal ulcers, short term treatment of active benign gastric ulcers, short term treatment of active erosive esophagitis, maintenance of healing of erosive esophagitis, pathological hypersecretory conditions including Zollinger- Ellison Syndrome, H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Attributes

  • Indications:
    • Short term treatment of active duodenal ulcer
    • Maintenance of healed duodenal ulcers
    • Short term treatment of active benign gastric ulcers
    • Short term treatment of active erosive esophagitis
    • Maintenance of healing of erosive esophagitis
    • Pathological hypersecretory conditions including Zollinger- Ellison Syndrome
    • H. pylori eradication to reduce the risk of duodenal ulcer recurrence
  • Pharmacology: Substituted benzimidazole, PPI, blocks the final step of acid secretion by inhibiting H+/K+ ATPase enzyme system in gastric parietal cell
  • Dosage & Administration:
    • Benign gastric ulcer: 30 mg daily in the morning for 8 weeks
    • Duodenal ulcer: 30 mg daily in the morning for 4 weeks; maintenance 15 mg
    • NSAID-associated duodenal or gastric ulcer: 15-30 mg daily for 4 weeks, followed by a further 4 weeks if not fully healed
    • Zollinger-Ellison syndrome (and other hypersecretory conditions): Initially 60 mg once daily adjusted according to response; daily doses of 120 mg or more is given in two divided doses
    • Gastroesophageal reflux disease: 30 mg daily in the morning for 4 weeks, followed by a further 4 weeks if not fully healed; maintenance 15-30 mg daily
    • Acid-related dyspepsia: 15-30 mg daily in the morning for 2-4 weeks
  • Interaction: Selective inhibitor of cytochrome P-450 monooxygenase system, potential effect on hepatic clearance, uncertainty over effect on oral combined contraceptive pill, likely physiological changes similar to Omeprazole
  • Contraindications: Known hypersensitivity to any component of the formulation
  • Side Effects:
    • Possible induction of carcinoid tumors by profound acid suppression
    • Rise in serum gastrin levels
    • Long term treatment with a proton pump inhibitor in patients with Helicobacter pylori infection may accelerate the development of atrophic gastritis
    • Dose dependent diarrhea
    • Headache
  • Pregnancy & Lactation: Lansoprazole should be avoided in pregnancy unless there are compelling reasons
  • Precautions & Warnings:
    • Gastric malignancy should be ruled out
    • Hepatic impairment
    • Pregnancy and lactation
  • Use in Special Populations:
    • Neonates: Not recommended for use
    • Children: The youngest person to have received Lanozole in clinical trials was 13 years old
    • The Elderly: No increase in adverse drug reaction
  • Therapeutic Class: Proton Pump Inhibitor
  • Storage Conditions: Store at 25°C

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