Ketolac 0.5% (Ophthalmic Solution)
5 ml drop: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Nipa pharmaceuticals ltd |
| Also available as |
Title and Categories
- Ketolac
- Pharmaceutical Product
- NSAID
- Pain Relief
- Ophthalmic Solution
- Anti-Inflammatory Drug
- Analgesic Medication
- Post-Operative Pain Management
Dimensions
N/A
Color Options
N/A
Functions
- Short-term management of moderate to severe acute post-operative pain
- Relief of pain, inflammation, and light sensitivity after ocular surgery
- Decrease eye inflammation caused by seasonal allergies
Materials
- Ketorolac Tromethamine
- Pyrrolo-Pyrrole Compound
- Amino-Hydroxymethyl-Propanediol
Technical Specifications
- Chemical Name: 5-Benzoyle-2,3-Dihydro-1H-Pyrroligine-1-Carboxylic Acid
- Pharmacokinetic Property: Linear
- Metabolism: Largely in the liver
- Excretion: Mostly in urine
Design Elements
- Form: Oral Tablets
- Form: Eye Drops
- Injection Administration
- Mode of Action: Inhibit prostaglandin synthesis
- Minimal Anti-Inflammatory Effect at Analgesic Dose
Usability Features
- Recommended Dosage: 10 mg every 4-6 hours (Tablet)
- Recommended Dosage: Single or multiple doses for acute pain management (Injection)
- Analgesic Effect Onset: Within 30 minutes
- Duration of Analgesic Effect: 4 to 6 hours
- Not recommended for chronic use
- Contraindicated in children under 16 years of age
Indications
- Short-term management of post-operative pain
- Relief of pain, inflammation, and light sensitivity after ocular surgery
- Decrease in eye inflammation caused by seasonal allergies
Pharmacology
- Potent analgesic
- Inhibits cyclooxygenase enzyme system
- Demonstrates minimal anti-inflammatory effect at analgesic dose
Dosage & Administration
- Tablet Dosage: 10 mg every 4-6 hours
- Injection Dosage: Single or multiple doses for acute pain management
- Maximum Daily Dose: Not to exceed specified limits based on age, weight, and renal function
- Eye Drops Dosage: 1 drop in each eye 4 times daily
Interaction
- Increased side effects with other NSAIDs or aspirin
- Enhanced anti-coagulant effect with anti-coagulants
- Reduced anti-hypertensive effect with Beta Blockers
- Increased risk of renal impairment with ACE Inhibitors
- Enhanced toxicity of methotrexate
Contraindications
- Hypersensitivity to Ketorolac or other NSAIDs
- Children under 16 years of age
- Prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Melana
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in female
- Pulmonary edema
Pregnancy & Lactation
- Pregnancy category: C
- Avoid in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Exercise caution in patients over 65 years of age
- Caution in patients with active peptic ulcer, gastrointestinal bleeding, asthma, or liver dysfunction
- Discontinue use of topical NSAIDs in case of corneal epithelial breakdown
- Avoid administration while wearing contact lenses (Eye Drops)
Therapeutic Class
- Rheumatoid Arthritis Medications
- Non-Opioid Analgesics
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children