Minolac 60 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 95.65 (1 x 5: ৳ 478.25)

Medicine Details

Category Details
Generic Ketorolac tromethamine
Company Aci limited
Also available as
Minolac 10 mg tablet Minolac 30 mg injection

Indications

  • Management of moderate to severe acute post-operative pain
  • Relief of pain, inflammation, and light sensitivity after ocular surgery
  • Decrease in eye inflammation or redness caused by seasonal allergies

Description

  • Nonsteroidal anti-inflammatory drug (NSAID)
  • Inhibition of prostaglandin synthesis
  • Peripherally acting analgesic
  • Highly protein bound and largely metabolized in the liver

Pharmacology

  • Inhibition of cyclooxygenase enzyme system
  • Minimal anti-inflammatory effect at analgesic dose

Dosage & Administration

  • Recommended tablet dose of 10 mg every 4-6 hours
  • Short-term use only (up to 7 days)
  • Injection for management of moderately severe acute pain
  • Duration of analgesic effect usually 4 to 6 hours
  • Eye drops administration: 1 drop in each eye 4 times daily

Interaction

  • Increased side effects with other NSAIDs or aspirin
  • Enhanced anti-coagulant effect with anti-coagulants
  • Reduction in anti-hypertensive effect with beta blockers
  • Increased risk of renal impairment with ACE inhibitors
  • Enhanced toxicity of methotrexate

Contraindications

  • Hypersensitivity to the drug or other NSAIDs
  • Use in children under 16 years of age
  • Prophylactic analgesic use before surgery

Side Effects

  • Nausea
  • Vomiting
  • Gastro-intestinal bleeding
  • Melana
  • Peptic ulcer
  • Pancreatitis
  • Anxiety
  • Drowsiness
  • Headache
  • Excessive thirst
  • Fatigue
  • Bradycardia
  • Hypertension
  • Palpitation
  • Chest pain
  • Infertility in female
  • Pulmonary edema

Pregnancy & Lactation

  • FDA Pregnancy category C
  • Avoidance in pregnancy and lactation unless benefits outweigh risks

Precautions & Warnings

  • Caution in patients over the age of 65 years
  • Caution in patients with active or suspected peptic ulcer or gastrointestinal bleeding, asthma, and liver dysfunction
  • Discontinue use in patients with evidence of corneal epithelial breakdown
  • No administration while wearing contact lenses

Therapeutic Class

  • Drugs used for Rheumatoid Arthritis
  • Non-Opioid Analgesics

Storage Conditions

  • Dry place away from light and heat
  • Keep out of the reach of children

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