K-Lac 60 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 95.00

Medicine Details

Category Details
Generic Ketorolac tromethamine
Company Ethical drugs limited
Also available as
K lac 30 mg injection K lac 10 mg tablet

Indications

  • Short-term management of post-operative pain
  • Relief of pain, inflammation, and light sensitivity after ocular surgery
  • Decrease eye inflammation or redness caused by seasonal allergies

Description

  • Pyrrolo-pyrrole group nonsteroidal anti-inflammatory drug (NSAID)
  • Chemical name: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid
  • Mode of action associated with the S-form
  • Highly protein bound
  • Metabolized in the liver

Pharmacology

  • Inhibits cyclooxygenase enzyme system
  • Minimal anti-inflammatory effect at analgesic dose

Dosage & Administration

  • Tablet: Recommended dose is 10 mg every 4-6 hours for short-term use
  • Injection: Used for management of moderately severe, acute pain
  • IM administration should be given slowly and deeply into the muscle
  • IV bolus must be given over no less than 15 seconds
  • Recommended dosages for different age groups and conditions

Interaction

  • Other NSAIDs or aspirin can increase side effects
  • Anti-coagulants can enhance anti-coagulant effect
  • Beta Blocker may reduce anti-hypertensive effect
  • ACE Inhibitors can increase risk of renal impairment
  • Methotrexate can enhance the toxicity of methotrexate

Contraindications

  • Hypersensitivity to the drug or other NSAIDs
  • Children under 16 years of age
  • Prophylactic analgesic use before surgery

Side Effects

  • Nausea
  • Vomiting
  • Gastro-intestinal bleeding
  • Melana
  • Peptic ulcer
  • Pancreatitis
  • Anxiety
  • Drowsiness
  • Headache
  • Excessive thirst
  • Fatigue
  • Bradycardia
  • Hypertension
  • Palpitation
  • Chest pain
  • Infertility in females
  • Pulmonary edema

Pregnancy & Lactation

Category C drug, should be avoided in pregnancy and lactation unless the potential benefits outweigh the possible risks to the fetus

Precautions & Warnings

Caution in patients over 65 years, with active/suspected peptic ulcer or gastrointestinal bleeding, asthma, and liver dysfunction

Therapeutic Class

Drugs used for Rheumatoid Arthritis, Non-Opioid Analgesics

Storage Conditions

Keep in a dry place away from light and heat, out of reach of children

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