Eurolac 30 mg/ml (IM/IV Injection)

1 ml ampoule: ৳ 55.00

Medicine Details

Category

  • Pain Management
  • Ophthalmic Solution
  • Nonsteroidal Anti-inflammatory Drug
  • Analgesic
  • Anti-inflammatory
  • Ocular Surgery
  • Allergy Relief
  • Rheumatoid Arthritis

Pharmacological class

  • Nonsteroidal Anti-inflammatory Drug
  • Analgesic
  • Cyclooxygenase Inhibitor
  • Pyrrolo-pyrrole Group

Dosage form

  • Tablet
  • Injection
  • Eye Drops

Active ingredient

Ketorolac Tromethamine

Chemical name

5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)

Mechanism of action

Inhibition of Prostaglandin Synthesis

Protein binding

Highly Protein Bound

Metabolism

  • Liver Metabolism
  • Metabolites excreted in Urine

Recommended dosage

  • Tablet: 10 mg every 4-6 hours for short-term use (up to 7 days)
  • Injection:
    • Single dose treatment:
      • IM dosing:
        • 60 mg for patients <65 years of age
        • 30 mg for patients >65 years of age, renally impaired, or <50 kg of body weight
      • IV dosing:
        • 30 mg for patients <65 years of age
        • 15 mg for patients >65 years of age, renally impaired, or <50 kg of body weight
      • Age 2 16 years:
        • IM dosing: 1 mg/kg up to a max of 30 mg
        • IV dosing: 0.5 mg/kg up to a max of 15 mg
    • Multiple dose treatment:
      • 30 mg every 6 hours for patients <65 years of age, max daily dose 120 mg
      • 15 mg every 6 hours for patients >65 years of age, renally impaired, or <50 kg, max daily dose 60 mg
    • Conversion to oral therapy: Total combined daily dose of ketorolac (oral + parenteral) should not exceed 120 mg in younger adult patients or 60 mg in elderly patients. Oral dosing should not exceed 40 mg
  • Eye drops: 1 drop in each eye 4 times daily

Interactions

  • Other NSAIDs or aspirin
  • Anti-coagulants
  • Beta Blockers
  • ACE Inhibitors
  • Methotrexate

Contraindications

  • Hypersensitivity to Ketorolac or other NSAIDs
  • Children under 16 years of age
  • Prophylactic analgesic before surgery

Side effects

  • Nausea
  • Vomiting
  • Gastro-intestinal bleeding
  • Melena
  • Peptic ulcer
  • Pancreatitis
  • Anxiety
  • Drowsiness
  • Headache
  • Excessive thirst
  • Fatigue
  • Bradycardia
  • Hypertension
  • Palpitation
  • Chest pain
  • Infertility in females
  • Pulmonary edema

Pregnancy lactation

FDA Pregnancy category C. Avoid use in pregnancy and lactation unless benefits outweigh risks

Precautions warnings

  • Age over 65 years
  • Active or suspected peptic ulcer or gastrointestinal bleeding
  • Asthma
  • Liver dysfunction
  • Corneal health monitoring for topical NSAID use

Therapeutic class

  • Rheumatoid Arthritis Drugs
  • Non-Opioid Analgesics

Storage conditions

Keep in a dry place away from light and heat, out of the reach of children

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