Ofpain 60 mg/2 ml (IM/IV Injection)
2 ml ampoule: ৳ 95.29
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Kemiko pharmaceuticals ltd |
| Also available as |
Indications
- Management of moderate to severe post-operative pain
- Relief of pain, inflammation, and light sensitivity after ocular surgery
- Decrease eye inflammation and redness from seasonal allergies
Description
- Chemical composition: pyrrolo-pyrrole group of NSAID
- Inhibition of prostaglandin synthesis
- Metabolized in liver
- Excretion in urine
Pharmacology
- Inhibition of cyclooxygenase enzyme system
- Minimal anti-inflammatory effect at analgesic dose
Dosage & Administration
- Tablet recommended dose: 10 mg every 4-6 hours for up to 7 days
- Injection for acute pain management post-surgery: IV/IM dosing for adults and children
- Eye drops dosage: 1 drop in each eye 4 times daily
Interaction
- Increased side effects with other NSAIDs or aspirin
- Enhanced anti-coagulant effect with anti-coagulants
- Reduced anti-hypertensive effect with beta blockers
- Increased risk of renal impairment with ACE Inhibitors
- Enhanced toxicity of methotrexate
Contraindications
- Hypersensitivity to ketorolac or other NSAIDs
- Children under 16 years
- Prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastrointestinal bleeding
- Melena
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in female
- Pulmonary edema
Pregnancy & Lactation
- FDA Pregnancy category: C
- Avoidance in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Caution in patients over 65 years
- Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
- Discontinue eye drops if corneal epithelial breakdown is detected
- Avoid use while wearing contact lenses
Therapeutic Class
- Rheumatoid Arthritis drugs
- Non-Opioid Analgesics
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children