Ketonaaf 10 mg (Tablet)
Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Naafco pharma ltd |
Indications
- Short-term management of moderate to severe acute post-operative pain
- Relieves pain, inflammation, and light sensitivity after ocular surgery
- Decreases eye inflammation or redness caused by seasonal allergies
Description
- Drug of pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drug (NSAID)
- Chemical composition: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
- Inhibits synthesis of prostaglandins and acts as a peripherally acting analgesic
Pharmacology
- Potent analgesic of the non-steroidal anti-inflammatory drugs (NSAIDs)
- Inhibits the cyclooxygenase enzyme system and prostaglandin synthesis
- Minimal anti-inflammatory effect at analgesic dose
Dosage & Administration
- Recommended tablet dose: 10 mg every 4-6 hours for short-term use only (up to 7 days)
- Injection for acute pain management on a regular or as-needed schedule
- Different dosage recommendations based on age and weight
- Single-dose and multiple-dose treatment guidelines
- Specific dosage recommendations for eye drops
Interaction
- NSAIDs or aspirin increase side effects of Ketonaaf
- Anti-coagulants enhance anti-coagulant effect
- Beta Blockers reduce the anti-hypertensive effect
- ACE Inhibitors increase the risk of renal impairment
- Methotrexate enhances the toxicity of methotrexate
Contraindications
- Hypersensitivity to Ketorolac or other NSAIDs
- Not suitable for use in children under 16 years of age
- Contraindicated as prophylactic analgesic before surgery
Side Effects
- Nausea, vomiting, and gastrointestinal bleeding
- Melana, peptic ulcer, and pancreatitis
- Anxiety, drowsiness, and headache
- Excessive thirst, fatigue, and bradycardia
- Hypertension, palpitation, and chest pain
- Infertility in females and pulmonary edema
Pregnancy & Lactation
- US FDA Pregnancy category: C
- Avoid use in pregnancy and lactation unless benefits outweigh risks to the fetus
Precautions & Warnings
- Caution in patients over the age of 65 years
- Caution for patients with peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
- Warning for patients with corneal epithelial breakdown when using eye drops
Therapeutic Class
- Drugs used for Rheumatoid Arthritis
- Non-opioid analgesics
Storage Conditions
- Store in a dry place away from light and heat
- Keep out of the reach of children