Ketonaaf 10 mg (Tablet)

Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00

Medicine Details

Category Details
Generic Ketorolac tromethamine
Company Naafco pharma ltd

Indications

  • Short-term management of moderate to severe acute post-operative pain
  • Relieves pain, inflammation, and light sensitivity after ocular surgery
  • Decreases eye inflammation or redness caused by seasonal allergies

Description

  • Drug of pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drug (NSAID)
  • Chemical composition: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
  • Inhibits synthesis of prostaglandins and acts as a peripherally acting analgesic

Pharmacology

  • Potent analgesic of the non-steroidal anti-inflammatory drugs (NSAIDs)
  • Inhibits the cyclooxygenase enzyme system and prostaglandin synthesis
  • Minimal anti-inflammatory effect at analgesic dose

Dosage & Administration

  • Recommended tablet dose: 10 mg every 4-6 hours for short-term use only (up to 7 days)
  • Injection for acute pain management on a regular or as-needed schedule
  • Different dosage recommendations based on age and weight
  • Single-dose and multiple-dose treatment guidelines
  • Specific dosage recommendations for eye drops

Interaction

  • NSAIDs or aspirin increase side effects of Ketonaaf
  • Anti-coagulants enhance anti-coagulant effect
  • Beta Blockers reduce the anti-hypertensive effect
  • ACE Inhibitors increase the risk of renal impairment
  • Methotrexate enhances the toxicity of methotrexate

Contraindications

  • Hypersensitivity to Ketorolac or other NSAIDs
  • Not suitable for use in children under 16 years of age
  • Contraindicated as prophylactic analgesic before surgery

Side Effects

  • Nausea, vomiting, and gastrointestinal bleeding
  • Melana, peptic ulcer, and pancreatitis
  • Anxiety, drowsiness, and headache
  • Excessive thirst, fatigue, and bradycardia
  • Hypertension, palpitation, and chest pain
  • Infertility in females and pulmonary edema

Pregnancy & Lactation

  • US FDA Pregnancy category: C
  • Avoid use in pregnancy and lactation unless benefits outweigh risks to the fetus

Precautions & Warnings

  • Caution in patients over the age of 65 years
  • Caution for patients with peptic ulcer, gastrointestinal bleeding, asthma, and liver dysfunction
  • Warning for patients with corneal epithelial breakdown when using eye drops

Therapeutic Class

  • Drugs used for Rheumatoid Arthritis
  • Non-opioid analgesics

Storage Conditions

  • Store in a dry place away from light and heat
  • Keep out of the reach of children

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