Lansopril 30 mg (Capsule (Enteric Coated))

Unit Price: ৳ 5.50 (30's pack: ৳ 165.00)

Medicine Details

Category Details
Generic Lansoprazole
Company Amico laboratories ltd

Indications

  • Short term treatment of active duodenal ulcer
  • Maintenance of healed duodenal ulcers
  • Short term treatment of active benign gastric ulcers
  • Short term treatment of active erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Pathological hypersecretory conditions including Zollinger- Ellison Syndrome
  • H. pylori eradication to reduce the risk of duodenal ulcer recurrence

Pharmacology

Substituted benzimidazole, PPI, inhibits H+/K+ ATPase enzyme system in gastric parietal cell

Dosage & Administration

  • Benign gastric ulcer: 30 mg daily in the morning for 8 weeks
  • Duodenal ulcer: 30 mg daily in the morning for 4 weeks; maintenance 15 mg
  • NSAID-associated duodenal or gastric ulcer: 15-30 mg daily for 4 weeks, followed by a further 4 weeks if not fully healed
  • Zollinger-Ellison syndrome: Initially 60 mg once daily adjusted according to response; daily doses of 120 mg or more is given in two divided doses
  • Gastroesophageal reflux disease: 30 mg daily in the morning for 4 weeks, followed by a further 4 weeks if not fully healed; maintenance 15-30 mg daily
  • Acid-related dyspepsia: 15-30 mg daily in the morning for 2-4 weeks

Interaction

Selective inhibitor of cytochrome P-450 monooxygenase system, uncertain effect on oral combined contraceptive pill

Contraindications

Known hypersensitivity to any component of the formulation

Side Effects

  • Induction of carcinoid tumors by profound acid suppression
  • Rise in serum gastrin levels
  • Dose dependent diarrhea
  • Headache

Pregnancy & Lactation

Avoid in pregnancy unless compelling reasons

Precautions & Warnings

  • Gastric malignancy should be ruled out
  • Hepatic impairment
  • Pregnancy and lactation

Use in Special Populations

  • Neonates: Not recommended
  • Children: The youngest person to have received Lansopril in clinical trials was 13 years old
  • The Elderly: No increase in adverse drug reaction

Therapeutic Class

Proton Pump Inhibitor

Storage Conditions

Store at 25° C

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