Kelorac 30 mg/ml (IM/IV Injection)

1 ml ampoule: ৳ 55.00 (1 x 5: ৳ 275.00)

Medicine Details

Category Details
Generic Ketorolac tromethamine
Company One pharma ltd
Also available as
Kelorac 10 mg tablet

Indications

  • Short-term management of moderate to severe acute post-operative pain
  • Relief of pain, inflammation, and light sensitivity after ocular surgery
  • Decrease eye inflammation or redness caused by seasonal allergies

Description

  • Belongs to pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drug (NSAID)
  • Chemical name: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
  • Inhibits synthesis of prostaglandins
  • Metabolized in the liver

Pharmacology

  • Potent analgesic of the non-steroidal anti-inflammatory drugs (NSAIDs)
  • Inhibits the cyclooxygenase enzyme system
  • Minimal anti-inflammatory effect at analgesic dose

Dosage & Administration

  • Tablet recommended dose: 10 mg every 4-6 hours for short-term use only (up to 7 days)
  • Injection for management of moderately severe, acute pain at opioid level
  • Recommended eye drop dosage: 1 drop in each eye 4 times daily

Interaction

  • Other NSAIDs or aspirin: Increase side effects of Kelorac
  • Anti-coagulants: Enhance anti-coagulant effect
  • Beta Blocker: Reduce anti-hypertensive effect
  • ACE Inhibitors: Increase risk of renal impairment
  • Methotrexate: Enhance toxicity of methotrexate

Contraindications

  • Hypersensitivity to this drug or other NSAIDs
  • Children under 16 years of age
  • Prophylactic analgesic before surgery

Side Effects

  • Nausea
  • Vomiting
  • Gastro-intestinal bleeding
  • Melena
  • Peptic ulcer
  • Pancreatitis
  • Anxiety
  • Drowsiness
  • Headache
  • Excessive thirst
  • Fatigue
  • Bradycardia
  • Hypertension
  • Palpitation
  • Chest pain
  • Infertility in females
  • Pulmonary edema

Pregnancy & Lactation

  • Pregnancy category: C
  • Avoided in pregnancy and lactation unless benefits outweigh risks to the fetus

Precautions & Warnings

  • Caution in patients over 65 years
  • Caution in patients with active or suspected peptic ulcer or gastrointestinal bleeding
  • Caution in patients with asthma and liver dysfunction
  • Discontinue use in cases of corneal epithelial breakdown
  • Not to be administered while wearing contact lenses

Therapeutic Class

  • Drugs used for Rheumatoid Arthritis
  • Non-Opioid Analgesics

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Related Brands