Troket 10 mg (Tablet)

Unit Price: ৳ 10.00

Medicine Details

Category Details
Generic Ketorolac tromethamine
Company Orbit pharmaceuticals ltd

Indications

  • Short-term management of moderate to severe acute post-operative pain
  • Relieving pain, inflammation, and light sensitivity after ocular surgery
  • Decreasing eye inflammation or redness caused by seasonal allergies

Description

  • Belongs to the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAID)
  • Chemical composition: 5 benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2 - amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
  • Inhibits synthesis of prostaglandins
  • Biological activity associated with the S-form
  • Linear pharmacokinetic property
  • Highly protein bound
  • Largely metabolized in liver

Pharmacology

  • Potent analgesic of the non-steroidal anti-inflammatory drugs (NSAIDs)
  • Inhibits the cyclooxygenase enzyme system
  • Minimal anti-inflammatory effect at analgesic dose

Dosage & Administration

  • Tablet: Recommended dose is 10 mg every 4-6 hours for short-term use (up to 7 days)
  • Injection: Can be used for moderate to severe acute pain on a regular or as-needed schedule
  • IV bolus must be given over no less than 15 seconds
  • Duration of analgesic effect is usually 4 to 6 hours
  • Specific dosing guidelines for different age groups and conditions

Interaction

  • Other NSAIDs or aspirin: Increases the side effects of Troket
  • Anti-coagulants: Enhance anti-coagulant effect
  • Beta Blocker: Reduces the anti-hypertensive effect
  • ACE Inhibitors: Increases the risk of renal impairment
  • Methotrexate: Enhances the toxicity of methotrexate

Contraindications

  • Hypersensitivity to Ketorolac or other NSAIDs
  • Not recommended for use in children under 16 years of age
  • Contraindicated as prophylactic analgesic before surgery

Side Effects

  • Nausea
  • Vomiting
  • Gastro-intestinal bleeding
  • Melana
  • Peptic ulcer
  • Pancreatitis
  • Anxiety
  • Drowsiness
  • Headache
  • Excessive thirst
  • Fatigue
  • Bradycardia
  • Hypertension
  • Palpitation
  • Chest pain
  • Infertility in females
  • Pulmonary edema

Pregnancy & Lactation

  • US FDA Pregnancy category: C
  • Should be avoided in pregnancy and lactation unless the potential benefits outweigh the possible risks to the fetus

Precautions & Warnings

  • Caution in patients over the age of 65 years
  • Caution in patients with active or suspected peptic ulcer or gastrointestinal bleeding
  • Caution in patients with asthma and liver dysfunction
  • Patients with evidence of corneal epithelial breakdown should immediately discontinue use of topical NSAIDs

Therapeutic Class

  • Drugs used for Rheumatoid Arthritis
  • Non-Opioid Analgesics

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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