Lazo 30 mg (Capsule (Enteric Coated))

Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Lansoprazole
Company Desh pharmaceuticals ltd

Indications

  • Short term treatment of active duodenal ulcer
  • Maintenance of healed duodenal ulcers
  • Short term treatment of active benign gastric ulcers
  • Short term treatment of active erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Pathological hypersecretory conditions including Zollinger-Ellison Syndrome
  • H. pylori eradication to reduce the risk of duodenal ulcer recurrence

Pharmacology

Substituted benzimidazole, PPI, inhibits acid secretion by inhibiting H+/K+ ATPase enzyme system in gastric parietal cell

Dosage & Administration

  • 30 mg daily in the morning for benign gastric ulcer for 8 weeks
  • 30 mg daily in the morning for duodenal ulcer for 4 weeks; maintenance 15 mg
  • 15-30 mg daily for NSAID-associated duodenal or gastric ulcer for 4 weeks
  • Initially 60 mg once daily for Zollinger-Ellison syndrome, adjusted according to response
  • 30 mg daily in the morning for gastroesophageal reflux disease for 4 weeks; maintenance 15-30 mg daily
  • 15-30 mg daily in the morning for acid-related dyspepsia for 2-4 weeks

Interaction

Selective inhibitor of the cytochrome P-450 monooxygenase system, uncertain effect on the oral combined contraceptive pill, physiological changes similar to those found with Omeprazole

Contraindications

Known hypersensitivity to any component of the formulation

Side Effects

  • Possible induction of carcinoid tumors by profound acid suppression
  • Rise in serum gastrin levels in the first 3 months of treatment
  • Dose dependent diarrhea
  • Incidence of headache in treated patients

Pregnancy & Lactation

Lansoprazole should be avoided in pregnancy unless there are compelling reasons

Precautions & Warnings

  • Gastric malignancy should be ruled out
  • Hepatic impairment
  • Pregnancy and lactation

Use in Special Populations

  • Not recommended for use in neonates
  • The youngest person to have received Lazo in clinical trials was 13 years old
  • No increase in adverse drug reaction in the elderly

Therapeutic Class

Proton Pump Inhibitor

Storage Conditions

Store at 25°C

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