Detonix 20 mg (Tablet (Enteric Coated))

Unit Price: ৳ 4.00 (10 x 15: ৳ 600.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Pantoprazole sodium
Company Desh pharmaceuticals ltd

Indications

  • Peptic ulcer diseases
  • Gastroesophageal reflux diseases
  • Ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs)
  • Eradication of Helicobacter pylori (in combination with antibiotics)
  • Zollinger-Ellison Syndrome

Pharmacology

  • Proton pump inhibitor
  • Suppresses final step in gastric acid production
  • Covalently binds to H+/K+ATPase enzyme system

Dosage & Administration

  • Oral administration
  • Benign gastric ulcer: 40 mg daily in the morning for 4 weeks
  • Gastro-esophageal reflux disease: 20-40 mg daily in the morning for 4 weeks
  • Duodenal ulcer: 40 mg daily in the morning for 2 weeks
  • IV Injection: 40 mg once daily for duodenal ulcer and gastric ulcer, 40 mg once daily for 7-10 days for prevention of rebleeding in peptic ulcer
  • Long-term management: 80 mg IV every 12 hours for Zollinger-Ellison Syndrome

Interaction

  • No significant drug interactions observed in clinical studies

Contraindications

  • Known hypersensitivity to any components of the formulation

Side Effects

  • Well tolerated in both short-term and long-term treatment
  • Common side effects: headache, diarrhea
  • Rare side effects: abdominal pain, flatulence, rash, insomnia, hyperglycemia

Pregnancy & Lactation

  • US FDA Pregnancy Category: B
  • No adequate and well-controlled studies in pregnant women
  • Excreted in human milk

Precautions & Warnings

  • Tablet should not be split, chewed, or crushed
  • Long-term therapy may lead to malabsorption of cyanocobalamin (Vitamin B12)
  • Increased risk of osteoporosis related disorders

Overdose Effects

  • No known symptoms of overdosage in humans
  • Highly protein bound, not readily dialyzable

Therapeutic Class

  • Proton Pump Inhibitor

Reconstitution

  • IV injection should be given as a slow intravenous injection
  • IV infusion should be given over a period of approximately 15 minutes

Storage Conditions

  • Keep in a dry place, away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15F2N3O4S
  • Chemical Structure: (Image of chemical structure)

Common Questions

  • What is Detonix 20 mg Tablet?
  • How long do I need to use Detonix 20 mg Tablet before I see improvement in my condition?
  • At what frequency do I need to use Detonix 20 mg Tablet?
  • Should I use Detonix 20 mg Tablet empty stomach, before food or after food?
  • What are the instructions for the storage and disposal of Detonix 20 mg Tablet?
  • What are the effects of Detonix 20 mg Tablet on older adults?
  • How long does it take for Detonix 20 mg Tablet to work?
  • Is Detonix 20 mg Tablet safe?
  • Does Detonix 20 mg Tablet cause weight gain?
  • What are the side effects of Detonix 20 mg Tablet?
  • Can I take Detonix 20 mg Tablet if I am pregnant or breastfeeding?
  • What should I do if I miss a dose of Detonix 20 mg Tablet?

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