Neurocet 500 mg (Tablet)
Unit Price: ৳ 30.00 (3 x 10: ৳ 900.00)
Strip Price: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Levetiracetam |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of partial-onset seizures
- Treatment of myoclonic seizures
- Treatment of primary generalized tonic-clonic seizures
- Monotherapy in adults and adolescents
- Adjunctive therapy in adults, adolescents, children, and infants
- Newly diagnosed epilepsy
- Juvenile Myoclonic Epilepsy
- Idiopathic Generalised Epilepsy
Description
- Precise mechanism of action unknown
- Minimal activity in submaximal stimulation
- Protection against secondarily generalized activity
- Inhibition of burst firing
- Selective prevention of hyper synchronization
Dosage
- Recommended starting dose of 250 mg twice daily for adults and adolescents
- Initial therapeutic dose of 500 mg twice daily
- Maximum dose of 1500 mg twice daily
- Dose adjustments for pediatric population
Administration
- Oral administration
- Swallowed with liquid
- Can be taken with or without food
- Administered in two equally divided doses
Interaction
- No influence on serum concentrations of existing antiepileptic medicinal products
- No influence on pharmacokinetics of existing antiepileptic medicinal products
- Interaction with Probenecid, Methotrexate, and Laxatives
- No alteration of absorption by food
- Slightly reduced rate of absorption by food
- No available data on interaction with alcohol
Contraindications
- Hypersensitivity to the active substance or other pyrrolidone derivatives or excipients
Side Effects
- Most common adverse reactions
- Incidence ≥ 5% more than placebo
- Different adverse reactions in adult and pediatric patients
Pregnancy & Lactation
- Not recommended during pregnancy
- Not recommended during breastfeeding
- Potential impact on fertility unknown
- Clinical data on impact unknown
Precautions & Warnings
- Dose adjustment for renal impairment
- Rare cases of decreased blood cell counts
- Potential association with acute kidney injury
- Potential association with suicidal thoughts and behavior
- Adapted formulation for pediatric population
- Long term effects on pediatric population unknown
Use in Special Populations
- Dose adjustment in elderly patients with compromised renal function
- Individualized dose according to renal function
- No dose adjustment in patients with mild to moderate hepatic impairment
- Dose adjustment in severe hepatic impairment
Overdose Effects
- Observation of somnolence, agitation, aggression, and respiratory depression
- No specific antidote available
- Symptomatic treatment required
- Potential need for haemodialysis
Therapeutic Class
Adjunct anti-epileptic drugs
Storage Conditions
Store at a cool temperature (not exceeding 25°C), dry place, protected from light