Aldopa 100 mg+10 mg (Tablet)

Unit Price: ৳ 7.00 (5 x 10: ৳ 350.00)
Strip Price: ৳ 70.00

Medicine Details

Indications

  • Treatment of Parkinson's disease
  • Management of rigidity and bradykinesia
  • Relief of tremor, dysphagia, sialorrhea
  • Postural instability management

Description

  • Levodopa as dopamine metabolic precursor
  • Carbidopa as DDC inhibitor
  • Blood-brain barrier crossing for Levodopa

Dosage & Administration

  • Initiation dosage for 100/10 mg tablet
  • Titration for optimum carbidopa dosage
  • Starting dose for 250/25 mg tablet
  • Maintenance dose individualization
  • Maximum daily dosage of Carbidopa

Interaction

  • Postural hypotension with antihypertensives
  • Concomitant use of tricyclic antidepressants
  • Bioavailability with ferrous sulphate or gluconate
  • Impact of dopamine-2 receptor antagonists
  • Interactions with isoniazid, phenytoin, and papaverine
  • Severe orthostatic hypotension with selegiline

Contraindications

  • Hypersensitivity to Carbidopa and Levodopa
  • Narrow-angle glaucoma
  • History of suspicious undiagnosed skin lesions or melanoma

Side Effects

  • Dyskinesias and involuntary movements
  • Nausea
  • Cardiovascular effects: palpitation, orthostatic issues
  • Gastrointestinal effects: vomiting, bleeding, ulcer
  • Hematologic effects: leukopenia, anemia, thrombocytopenia
  • Nervous system effects: dizziness, somnolence, hallucinations
  • Respiratory and skin effects
  • Urogenital effects

Pregnancy & Lactation

  • Unknown effects on human pregnancy
  • Possible hazards in women of childbearing potential
  • Excretion in human milk

Precautions & Warnings

  • Not recommended for medicine-induced reactions
  • Care in patients with cardiovascular or pulmonary disease
  • Cautious administration in patients with glaucoma
  • Monitoring of cardiac function in specific patients

Use in Special Populations

  • Safety and effectiveness in children not established
  • Not recommended for patients below 18 years

Therapeutic Class

  • Antiparkinson drugs

Storage Conditions

  • Cool and dry place, protected from light

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