Perkidopa 100 mg+10 mg (Tablet)

Unit Price: ৳ 7.00 (2 x 15: ৳ 210.00)
Strip Price: ৳ 105.00

Medicine Details

Indications

  • Treatment of Parkinson's disease and syndrome
  • Relieves rigidity and bradykinesia
  • Manages tremor, dysphagia, and postural instability

Description

  • Levodopa is the metabolic precursor of dopamine
  • Carbidopa is a dopa decarboxylase (DDC) inhibitor

Dosage & Administration

  • Dosage initiated with one tablet three or four times a day
  • Titration upward may be required in some patients
  • Initial dose for 250/25 mg tablet is one half taken once or twice daily

Interaction

  • Symptomatic postural hypotension may occur when added to antihypertensive medicines
  • Decrease in bioavailability when ingested with ferrous sulphate or ferrous gluconate

Contraindications

  • Hypersensitivity to Carbidopa and Levodopa
  • Narrow-angle glaucoma
  • History of malignant melanoma

Side Effects

  • Dyskinesias including choreiform and other involuntary movements
  • Nausea
  • Orthostatic effects including hypotensive episodes

Pregnancy & Lactation

  • Effects on human pregnancy are unknown
  • Hazardous effects on fetal development in rabbits
  • Unknown excretion in human milk

Precautions & Warnings

  • Not recommended for medicine-induced extrapyramidal reactions
  • Dosage reduction may be required for dyskinesias
  • Cautious administration to patients with severe cardiovascular or pulmonary disease

Use in Special Populations

  • Use in children below the age of 18 years is not recommended

Therapeutic Class

  • Antiparkinson drugs

Storage Conditions

  • Store in a cool and dry place, protected from light

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