Co-dopa CR 200 mg+50 mg (Tablet (Controlled Release))
Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Levodopa carbidopa cr tablet |
| Company | Unimed unihealth pharmaceuticals ltd |
| Also available as |
Indications
- Idiopathic Parkinson's disease
- Reduce off-period in patients treated with levodopa/decarboxylase inhibitors
- Reduce off-period in patients treated with levodopa alone
- Experienced motor fluctuations
Description
- Metabolic precursor of dopamine
- Crosses the blood-brain barrier
- Converted to dopamine in the brain
- Dopa decarboxylase (DDC) inhibitor
Dosage
- Initial recommended dose
- Dosage adjustments based on clinical response
- Recommended titration
- Substitution of treatment from conventional levodopa/decarboxylase inhibitor combinations
Administration
- Dosing intervals
- Maintenance
- Addition of other antiparkinson medication
- Interruption of therapy
Interaction
- Caution when administered concomitantly with other drugs
- Antihypertensive agents
- Antidepressants
- Anticholinergics
- Effect of iron
- Other drugs affecting therapeutic effects
Contraindications
- Sympathomimetic amine contraindication
- Contraindicated with non-selective monoamine oxidase (MAO) inhibitors
- Contraindicated with known hypersensitivity
- Contraindicated in patients with narrow-angle glaucoma
- Not to be used in patients with suspicious undiagnosed skin lesions or a history of melanoma
Side Effects
- Dyskinesia
- Nausea
- Hallucinations
- Dizziness
- Dry mouth
- Insomnia
- Depression
- Vomiting
- Anorexia
- Constipation
- Diarrhoea
- Weight loss
- Agitation
- Anxiety
- Fatigue
- Headache
- Rash
Pregnancy & Lactation
- Insufficient data for evaluation
- Excretion in human milk
- Not recommended during pregnancy and lactation
Precautions & Warnings
- Dyskinesias may occur in patients previously treated with levodopa alone
- Not recommended for drug-induced extrapyramidal reactions
- Monitoring of cardiac function
- Incidence of dyskinesias
- Monitoring for impulse control disorders
- Not recommended for use in children
Use in Special Populations
- Safety and effectiveness in children not established
- Not recommended for use in patients below the age of 18
Therapeutic Class
- Antiparkinson drugs
Storage Conditions
- Store in a cool and dry place
- Protected from light