Levolon 250 mg (Tablet)

Unit Price: ৳ 7.50 (20's pack: ৳ 150.00)

Medicine Details

Category Details
Generic Levofloxacin hemihydrate
Company Peoples pharma ltd
Also available as

Indications

  • Mild, moderate and severe infections treatment
  • Acute maxillary sinusitis treatment
  • Acute bacterial exacerbation of chronic bronchitis treatment
  • Community-acquired pneumonia treatment
  • Urinary tract infections treatment
  • Acute pyelonephritis treatment
  • Skin and soft tissue infections treatment
  • Enteric infections treatment

Description

  • Synthetic
  • Broad-spectrum
  • Fluoroquinolone derivative
  • Antibacterial agent for oral administration
  • Chiral fluorinated carboxyquinolone

Pharmacology

  • Broad-spectrum antibiotic
  • Inhibits bacterial topoisomerase IV and DNA gyrase
  • Required for DNA replication, transcription repair and recombination
  • In vitro activity against gm-ve and gm+ve microorganisms

Dosage

  • 250 mg or 500 mg or 750 mg strength
  • Oral administration
  • Can be taken without regard to food
  • Intravenous infusion for injection
  • Administration for acute sinusitis, exacerbation of chronic bronchitis, community-acquired pneumonia, urinary-tract infections, skin and soft-tissue infections, enteric fever, diarrhea, cholera, shigellosis & enteritis

Administration

  • Instructions for Levofloxacin Infusion
  • Check for leaks
  • Do not use if solution is cloudy or precipitate is present
  • Suspend container from hanger
  • Regulate rate of administration with flow control clamp

Interaction

  • Avoid co-administration with solutions containing multivalent cations
  • Reduced absorption with antacids, Iron and Adsorbents
  • Increased risk with NSAID and Warfarin

Contraindications

  • Hypersensitivity to levofloxacin
  • History of hypersensitivity to quinolone antimicrobial agents

Side Effects

  • Risk of retinal detachment
  • Nausea, vomiting, diarrhea, abdominal pain, flatulence
  • Rare occurrence of phototoxicity (0.1%)
  • Rare side-effects like tremors, depression, anxiety, confusion

Pregnancy & Lactation

  • Not recommended during pregnancy or nursing
  • Effects on the unborn child or nursing infant are unknown

Precautions & Warnings

  • Administered by slow intravenous infusion
  • Adequate water intake to avoid concentrated urine
  • Dose adjustment in renal insufficiency

Overdose Effects

  • Low potential for acute toxicity
  • Stomach should be emptied in case of acute overdosage
  • Patients should be kept under observation
  • Appropriate hydration should be maintained

Therapeutic Class

  • 4-Quinolone preparations

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Out of the reach of children

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