Pamel 40 mg (Tablet (Enteric Coated))

Unit Price: ৳ 6.00 (5 x 10: ৳ 300.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Pantoprazole sodium
Company Medicon pharmaceuticals ltd
Also available as
Pamel 20 mg tablet

Title

  • Pamel 40 mg Tablet

Categories

  • Medicine
  • Pharmaceuticals

Description

  • Proton Pump Inhibitor
  • Suppresses gastric acid production
  • Treats peptic ulcer diseases, GERD, ulcer induced by NSAIDs, eradication of Helicobacter pylori, Zollinger-Ellison Syndrome
  • Well tolerated in both short-term and long-term treatment
  • Common side effects: headache, diarrhea, abdominal pain, flatulance, rash, insomnia, hyperglycemia
  • FDA pregnancy category B
  • Caution: tablet should not be split, chewed, or crushed
  • May lead to malabsorption of Vitamin B12
  • May increase the risk of osteoporosis related disorders
  • No significant drug interactions observed in clinical studies
  • Contraindicated in patients with known hypersensitivity to any of the components of the formulation
  • Storage: Keep in a dry place, away from light and heat, out of the reach of children
  • Molecular Formula: C16H15F2N3O4S

Indications

  • Peptic ulcer diseases
  • Gastroesophageal reflux diseases
  • Ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs)
  • Eradication of Helicobacter pylori (in combination with antibiotics)
  • Zollinger-Ellison Syndrome

Pharmacology

  • Proton pump inhibitor
  • Suppresses final step in gastric acid production
  • Covalently binds to the H+/K+ ATPase enzyme system at the surface of the gastric parietal cell
  • Leads to inhibition of both basal and stimulated gastric acid secretion
  • Irrespective of the stimulus, effect persists longer than 24 hours

Dosage administration

  • Oral dosage for benign gastric ulcer: 40 mg daily in the morning for 4 weeks, may continue for further 4 weeks if not fully healed
  • Oral dosage for gastro-esophageal reflux disease: 20-40 mg daily in the morning for 4 weeks, may continue for further 4 weeks if not fully healed; maintenance dose is 20 mg daily, may be increased to 40 mg daily
  • Intravenous dosage for duodenal ulcer and gastric ulcer: 40 mg once daily for 7-10 days
  • Intravenous dosage for prevention of rebleeding in peptic ulcer: IV 80 mg, followed by 8 mg/hour infusion for 72 hours

Interaction

  • No significant drug interactions observed in clinical studies

Contraindications

  • Contraindicated in patients with known hypersensitivity to any of the components of the formulation

Side effects

  • Common side effects: headache, diarrhea, abdominal pain, flatulance, rash, insomnia, hyperglycemia

Pregnancy lactation

  • FDA pregnancy category B
  • No adequate and well-controlled studies in pregnant women
  • Excreted in human milk
  • Decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the benefit of the drug to the mother

Precautions warnings

  • Tablet should not be split, chewed, or crushed
  • Long-term therapy may lead to malabsorption of cyanocobalamin (Vitamin B12)
  • May increase the risk of osteoporosis related disorders

Overdose effects

  • No known symptoms of overdosage in humans

Reconstitution

  • IV injection should be given as a slow intravenous injection
  • Reconstituted solution may be stored at room temperature for a maximum of 4 hours
  • IV infusion should be given as an intravenous infusion over a period of approximately 15 minutes
  • Reconstituted solution may be stored at room temperature for a maximum of 4 hours prior to further dilution

Storage conditions

  • Keep in a dry place, away from light and heat, out of the reach of children

Chemical structure

  • Molecular Formula: C16H15F2N3O4S

Common questions

  • How long do I need to use Pamel 40 mg Tablet before I see improvement in my condition?
  • At what frequency do I need to use Pamel 40 mg Tablet?
  • Should I use Pamel 40 mg Tablet empty stomach, before food or after food?
  • What are the instructions for the storage and disposal of Pamel 40 mg Tablet?
  • What are the effects of Pamel 40 mg Tablet in older adults?
  • How long does it take for Pamel 40 mg Tablet to work?
  • Is Pamel 40 mg Tablet safe?
  • Does Pamel 40 mg Tablet cause weight gain?
  • What are the side effects of Pamel 40 mg Tablet?
  • Can I take Pamel 40 mg Tablet if I am pregnant or breastfeeding?
  • What should I do if I miss a dose of Pamel 40 mg Tablet?

Related Brands