Ezolid 600 mg (Tablet)
Unit Price: ৳ 85.00 (1 x 10: ৳ 850.00)
Strip Price: ৳ 850.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Linezolid |
| Company | Aci limited |
| Also available as |
Indications
- Treatment of nosocomial pneumonia
- Treatment of community-acquired pneumonia
- Treatment of complicated skin and skin structure infection
- Treatment of uncomplicated skin and skin structure infections
- Treatment of vancomycin-resistant Enterococcus faecium infections
Pharmacology
- Synthetic antibacterial agent
- In vitro activity against Gram-positive aerobic bacteria
- In vitro activity against some Gram-positive anaerobic bacteria
- In vitro activity against certain Gram-negative bacteria
- Inhibition of bacterial protein synthesis
- Binding to 23S ribosomal RNA
- Prevention of 70S initiation complex formation
Dosage & Administration
- Oral administration with or without food
- Intravenous administration over 30-120 minutes
- Dosage varies based on infection type and patient age
- No dose adjustment when switching from intravenous to oral administration
- Administration for different infections and patient groups
- Special dosing considerations for neonates
Interaction
- Interaction with reversible, nonselective inhibitor of monoamine oxidase
- Potential for interaction with adrenergic and serotonergic agents
- Avoidance of large quantities of foods or beverages with high tyramine content
Contraindications
- Contraindicated in patients with known hypersensitivity to Linezolid or components
- Contraindicated in patients taking monoamine oxidase inhibitors
- Contraindicated in patients with uncontrolled hypertension
- Contraindicated in patients with certain medical conditions
- Contraindicated in patients taking specific medications
Side Effects
- Most adverse events are mild to moderate
- Common adverse events include diarrhea, headache, and nausea
- Other reported adverse events including hypertension, dyspepsia, and pruritus
Pregnancy & Lactation
- Limited data on use during pregnancy
- Consideration of potential benefit vs. risk during pregnancy
- Presence in breast milk
- Consideration of developmental and health benefits of breastfeeding
Precautions & Warnings
- Weekly monitoring of complete blood counts
- Prompt ophthalmic evaluation for visual impairment symptoms
- Not approved for treatment of catheter-related infections
- Monitoring for Clostridium difficile-associated diarrhea
- Caution in patients with hypertension and sympathomimetic agents
- Monitoring for recurrent nausea, vomiting, and acidosis
- Monitoring for hypoglycemia
Overdose Effects
- No reported cases of overdose
- Symptomatic and supportive care advised
- Approximately 30% removal during 3 hours of haemodialysis
Therapeutic Class
- Belongs to macrolides therapeutic class
Reconstitution
- Shake well to reconstitute oral suspension
- Storage and use guidance for reconstituted suspension
- Intravenous administration recommendations and storage guidelines
Storage Conditions
- Store at room temperature (15°C-30°C)
- Store away from light and moisture
- Keep away from children