Ezolid 600 mg (Tablet)

Unit Price: ৳ 85.00 (1 x 10: ৳ 850.00)
Strip Price: ৳ 850.00

Medicine Details

Category Details
Generic Linezolid
Company Aci limited
Also available as

Indications

  • Treatment of nosocomial pneumonia
  • Treatment of community-acquired pneumonia
  • Treatment of complicated skin and skin structure infection
  • Treatment of uncomplicated skin and skin structure infections
  • Treatment of vancomycin-resistant Enterococcus faecium infections

Pharmacology

  • Synthetic antibacterial agent
  • In vitro activity against Gram-positive aerobic bacteria
  • In vitro activity against some Gram-positive anaerobic bacteria
  • In vitro activity against certain Gram-negative bacteria
  • Inhibition of bacterial protein synthesis
  • Binding to 23S ribosomal RNA
  • Prevention of 70S initiation complex formation

Dosage & Administration

  • Oral administration with or without food
  • Intravenous administration over 30-120 minutes
  • Dosage varies based on infection type and patient age
  • No dose adjustment when switching from intravenous to oral administration
  • Administration for different infections and patient groups
  • Special dosing considerations for neonates

Interaction

  • Interaction with reversible, nonselective inhibitor of monoamine oxidase
  • Potential for interaction with adrenergic and serotonergic agents
  • Avoidance of large quantities of foods or beverages with high tyramine content

Contraindications

  • Contraindicated in patients with known hypersensitivity to Linezolid or components
  • Contraindicated in patients taking monoamine oxidase inhibitors
  • Contraindicated in patients with uncontrolled hypertension
  • Contraindicated in patients with certain medical conditions
  • Contraindicated in patients taking specific medications

Side Effects

  • Most adverse events are mild to moderate
  • Common adverse events include diarrhea, headache, and nausea
  • Other reported adverse events including hypertension, dyspepsia, and pruritus

Pregnancy & Lactation

  • Limited data on use during pregnancy
  • Consideration of potential benefit vs. risk during pregnancy
  • Presence in breast milk
  • Consideration of developmental and health benefits of breastfeeding

Precautions & Warnings

  • Weekly monitoring of complete blood counts
  • Prompt ophthalmic evaluation for visual impairment symptoms
  • Not approved for treatment of catheter-related infections
  • Monitoring for Clostridium difficile-associated diarrhea
  • Caution in patients with hypertension and sympathomimetic agents
  • Monitoring for recurrent nausea, vomiting, and acidosis
  • Monitoring for hypoglycemia

Overdose Effects

  • No reported cases of overdose
  • Symptomatic and supportive care advised
  • Approximately 30% removal during 3 hours of haemodialysis

Therapeutic Class

  • Belongs to macrolides therapeutic class

Reconstitution

  • Shake well to reconstitute oral suspension
  • Storage and use guidance for reconstituted suspension
  • Intravenous administration recommendations and storage guidelines

Storage Conditions

  • Store at room temperature (15°C-30°C)
  • Store away from light and moisture
  • Keep away from children

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