Ocuflox 0.3% (Ophthalmic Solution)

5 ml drop: ৳ 70.00

Medicine Details

Category Details
Generic Lomefloxacin
Company Biopharma limited

Indications

  • Ocuflox ophthalmic preparation
  • bacterial infections
  • conjunctivitis
  • blepharitis
  • blepharoconjunctivitis
  • Staphylococcus aureus-induced corneal ulcers
  • Ocuflox susceptible germs

Pharmacology

  • Lomefloxacin
  • bacterial gyrase inhibitor
  • gram positive bacteria
  • gram negative bacteria
  • toxicity of Lomefloxacin
  • bacterial DNA processes
  • DNA replication
  • DNA transcription
  • DNA repairing
  • DNA recombination
  • DNA supercoiling
  • DNA relaxation
  • bacterial enzyme gyrase
  • A-subunit of bacterial enzyme gyrase
  • formation of stable complex
  • impairment of enzyme functions
  • killing of sensitive bacteria
  • cross-resistance with quinolones
  • clinical studies
  • efficacy in infections with chlamydia

Dosage

  • Adults dosage
  • Children dosage
  • frequency of application
  • duration of treatment

Administration

  • may be taken with food
  • may be taken without food

Interaction

  • ophthalmic preparations containing heavy metals
  • bacteriostatic ophthalmic antibiotics

Contraindications

  • Hypersensitivity
  • long term treatment with antibiotics
  • development of secondary fungal infections
  • growth of non susceptible bacteria

Side Effects

  • transient burning
  • phototoxicity
  • photosensitization
  • allergic reactions
  • asthma
  • dyspnoea
  • urticaria
  • erythema
  • pruritus
  • hypersensitization

Pregnancy & Lactation

  • passage through placenta barrier
  • excretion into maternal milk
  • clinical studies on human pregnancy
  • clinical studies on lactation

Precautions & Warnings

  • phototoxicity
  • exposure to sunlight
  • exposure to UV-radiation

Overdose Effects

  • risk of adverse effects due to accidental oral ingestion
  • contents of eye drop solution
  • recommended oral daily dose

Therapeutic Class

  • 4-Quinolone preparations
  • ophthalmic antibacterial drugs

Storage Conditions

  • temperature range for storage

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