Panto 40 mg (Tablet (Enteric Coated))

Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)

Strip Price: ৳ 60.00

Medicine Details

Category	Details
Generic	Pantoprazole sodium
Company	Somatec pharmaceuticals ltd
Also available as	Panto 20 mg tablet

Indications

Peptic ulcer diseases
Gastroesophageal reflux diseases
Ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs)
Eradication of Helicobacter pylori (in combination with antibiotics)
Zollinger-Ellison Syndrome

Pharmacology

Proton pump inhibitor that suppresses the final step in gastric acid production by covalently binding to the H+/K+ ATPase enzyme system

Dosage & Administration

Benign gastric ulcer: 40 mg daily in the morning for 4 weeks, continued for further 4 weeks, if not fully healed
Gastro-esophageal reflux disease: 20-40 mg daily in the morning for 4 weeks, continued for further 4 weeks, if not fully healed; maintenance dose is 20 mg daily, which may be increased to 40 mg daily
Duodenal ulcer: 40 mg daily in the morning for 2 weeks, continued for further 2 weeks if not fully healed
Duodenal ulcer associated with Helicobacter pylori: Pantoprazole is recommended at a dose of 40 mg twice daily in association with antimicrobial agents as detailed below: Amoxycillin 1 g and Clarithromycin 500 mg both twice daily for one week, or Clarithromycin 250 mg and Metronidazole 400 mg both twice daily for one week
Prophylaxis of NSAID-associated gastric or duodenal ulcer: 20 mg daily for those require long-term NSAID treatment
Zollinger-Ellison Syndrome: Initially 80 mg once daily adjusted according to response (elderly max. 40 mg daily); daily doses above 80 mg given in 2 divided doses

Interaction

No significant drug interactions observed in clinical studies

Contraindications

Pantoprazole is contraindicated in patients with known hypersensitivity to any of the components of the formulation

Side Effects

Headache
Diarrhea
Abdominal pain
Flatulence
Rash
Insomnia
Hyperglycemia

Pregnancy & Lactation

US FDA Pregnancy Category of Pantoprazole is B. It should be used during pregnancy only if clearly needed. Pantoprazole has been shown to be excreted in human milk

Precautions & Warnings

Panto tablet should not be split, chewed or crushed
Long-term therapy of Panto may lead to malabsorption of cyanocobalamin (Vitamin B12) or may increase the risk of osteoporosis related disorders

Overdose Effects

No known symptoms of overdosage in humans. Since Panto is highly protein bound, it is not readily dialyzable

Therapeutic Class

Proton Pump Inhibitor

Reconstitution

Panto lyophilized powder and 0.9% Sodium Chloride Injection is for intravenous administration only and must not be given by any other route
Panto IV infusion should be reconstituted with 10 ml of 0.9% Sodium Chloride Injection and further diluted with 0.9% Sodium Chloride Injection or 5% Dextrose or Lactated Ringer's Injection to a final volume of 100 ml

Storage Conditions

Keep in a dry place, away from light and heat. Keep out of the reach of children

Chemical Structure

Molecular Formula: C16H15F2N3O4S
Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-859-pantoprazole-sodium-chemical-structure-cnfmhAVGwpLzfJYlfu9P.svg

Common Questions about Panto 40 mg Tablet

What is Panto 40 mg Tablet?
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