Preslow 50 mg (Tablet)

Unit Price: ৳ 8.02 (5 x 10: ৳ 401.00)

Strip Price: ৳ 80.20

Medicine Details

Losartan Potassium is the first non-peptide orally active angiotensin II receptor blocker.

Usual starting and maintenance dose of 50 mg once daily for most patients
25 mg twice daily recommended prior to increasing the dose for inadequate antihypertensive effect
lower starting dose of 25 mg once daily recommended for patients over 75 years
Total daily dose ranges from 25 mg to 100 mg

Rifampicin and fluconazole reduce levels of active metabolite of Preslow
Concomitant use of Preslow and hydrochlorothiazide may lead to potentiation of the antihypertensive effects
Concomitant use of potassium-sparing diuretics, potassium supplements or salt substitutes containing potassium may lead to increases in serum potassium
The antihypertensive effect of losartan may be attenuated by the non-steroidal anti-inflammatory drug indomethacin
The use of ACE-inhibitor, angiotensin receptor antagonist, an anti-inflammatory drug and a thiazide diuretic at the same time increases the risk of renal impairment

Pregnancy Category D.

Avoid use during the second and third trimesters of pregnancy
Symptomatic hypotension may occur in volume-depleted patients
Significantly increased plasma concentration in cirrhotic patients
Changes in renal function including renal failure reported in renal impaired patient

No initial dosage adjustment necessary in patients with mild renal impairment
Lower starting dose recommended for moderate to severe renal impairment or patients on dialysis
Lower dose should be considered for patients with a history of hepatic impairment