Pantogen 20 mg (Tablet (Enteric Coated))
Medicine Details
Category | Details |
---|---|
Generic | Pantoprazole sodium |
Company | General pharmaceuticals ltd |
Also available as |
Indications
- Peptic ulcer diseases
- Gastroesophageal reflux diseases
- Ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs)
- Eradication of Helicobacter pylori (in combination with antibiotics)
- Zollinger-Ellison Syndrome
Pharmacology
Proton pump inhibitor that suppresses the final step in gastric acid production by covalently binding to the H+/K+ATPase enzyme system at the surface of the gastric parietal cell, leading to inhibition of both basal and stimulated gastric acid secretion, irrespective of the stimulus that persists longer than 24 hours
Dosage & Administration
- Benign gastric ulcer: 40 mg daily in the morning for 4 weeks, continued for further 4 weeks, if not fully healed
- Gastro-esophageal reflux disease: 20-40 mg daily in the morning for 4 weeks, continued for further 4 weeks, if not fully healed; maintenance dose is 20 mg daily, which may be increased to 40 mg daily
- Duodenal ulcer: 40 mg daily in the morning for 2 weeks, continued for further 2 weeks if not fully healed
- Duodenal ulcer associated with Helicobacter pylori: 40 mg twice daily in association with antimicrobial agents for one week
- Prophylaxis of NSAID-associated gastric or duodenal ulcer: 20 mg daily for long-term NSAID treatment
- Zollinger-Ellison Syndrome: Initially 80 mg once daily, adjusted according to response
- IV Injection for various conditions
Interaction
No significant drug interactions observed in clinical studies
Contraindications
Patients with known hypersensitivity to any of the components of the formulation
Side Effects
- Well tolerated in both short-term and long-term treatment
- Common side effects: headache, diarrhea
- Rare side effects: abdominal pain, flatulence, rash, insomnia, hyperglycemia
Pregnancy & Lactation
Category B; no adequate and well-controlled studies in pregnant women; excreted in human milk
Precautions & Warnings
- Tablet should not be split, chewed or crushed
- Long-term therapy may lead to malabsorption of cyanocobalamin (Vitamin B12) or increase risk of osteoporosis related disorders
Overdose Effects
No known symptoms of overdosage in humans; not readily dialyzable; symptomatic and supportive management recommended
Therapeutic Class
Proton Pump Inhibitor
Reconstitution
IV injection and IV infusion reconstitution directions provided
Storage Conditions
Keep in a dry place, away from light and heat; keep out of the reach of children
Chemical Structure
- Molecular Formula: C16H15F2N3O4S
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-859-pantoprazole-sodium-chemical-structure-cnfmhAVGwpLzfJYlfu9P.svg
Common Questions about Pantogen 20 mg Tablet
- What is Pantogen 20 mg Tablet?
- How long do I need to use Pantogen 20 mg Tablet before I see improvement in my condition?
- At what frequency do I need to use Pantogen 20 mg Tablet?
- Should I use Pantogen 20 mg Tablet empty stomach, before food or after food?
- What are the instructions for the storage and disposal of Pantogen 20 mg Tablet?
- What are the effects of Pantogen 20 mg Tablet on older adults?
- How long does it take for Pantogen 20 mg Tablet to work?
- Is Pantogen 20 mg Tablet safe?
- Does Pantogen 20 mg Tablet cause weight gain?
- What are the side effects of Pantogen 20 mg Tablet?
- Can I take Pantogen 20 mg Tablet if I am pregnant or breastfeeding?
- What should I do if I miss a dose of Pantogen 20 mg Tablet?
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