Lotemic T 0.5%+0.3% (Ophthalmic Suspension)

5 ml drop: ৳ 200.61

Medicine Details

Category Details
Generic Loteprednol etabonate tobramycin
Company Osl pharma limited

Indications for Use

  • Steroid-responsive inflammatory ocular conditions
  • Allergic conjunctivitis
  • Acne rosacea
  • Superficial punctate keratitis
  • Herpes zoster keratitis
  • Iritis
  • Cyclitis
  • Chronic anterior uveitis
  • Corneal injury from chemical, radiation or thermal burns
  • Post-operative inflammation following ocular surgery

Pharmacological Action

  • Loteprednol induction of phospholipase A2 inhibitory proteins
  • Inhibition of prostaglandins and leukotrienes biosynthesis
  • Tobramycin bactericidal activity
  • Inhibition of bacterial protein synthesis

Dosage and Administration

  • Shake well before use
  • Apply one drop into the conjunctival sac of the affected eye(s)
  • Every four to six hours dosing
  • Possible increase to every one to two hours for 24 to 48 hours

Interaction with Other Medications

  • Not detected in plasma following topical administration
  • Not expected to affect the pharmacokinetics of systemically administered medicinal products

Contraindications

  • Viral diseases of the cornea and conjunctiva
  • Known or suspected hypersensitivity to any of the ingredients
  • Hypersensitivity to other corticosteroids

Possible Side Effects

  • Increased intraocular pressure
  • Burning and stinging upon instillation
  • Vision disorders
  • Discharge
  • Itching
  • Lacrimation disorder
  • Photophobia
  • Corneal deposits
  • Ocular discomfort
  • Eyelid disorder
  • Unspecified eye disorders

Use in Pregnancy and Lactation

  • Use during pregnancy only if potential benefit justifies potential risk to the fetus
  • Caution during lactation

Precautions and Warnings

  • For ophthalmic use only
  • Monitor intraocular pressure if used for 10 days or longer
  • Risk of fungal infections of the cornea with prolonged use
  • Risk of overgrowth of nonsusceptible organisms with prolonged use
  • Possible cross-sensitivity to other aminoglycoside antibiotics

Use in Pediatric Patients

  • Safety and effectiveness not established in pediatric patients

Therapeutic Classification

  • Ophthalmic steroid - antibiotic combined preparations

Storage Conditions

  • Store at room temperature
  • Protect from light
  • Do not touch dropper tip to any surface
  • Use contents within four weeks after first opening
  • Protect from freezing

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