Panton-AX 40 mg (Tablet (Enteric Coated))

Unit Price: ৳ 9.00 (50's pack: ৳ 450.00)

Medicine Details

Category Details
Generic Pantoprazole sodium
Company Bristol pharmaceuticals ltd
Also available as
Panton ax 20 mg tablet

Indications

  • Peptic ulcer diseases
  • Gastroesophageal reflux diseases
  • Ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs)
  • Eradication of Helicobacter pylori (in combination with antibiotics)
  • Zollinger-Ellison Syndrome

Pharmacology

Proton pump inhibitor that suppresses the final step in gastric acid production by covalently binding to the H+/K+ATPase enzyme system at the surface of the gastric parietal cell. This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of the stimulus that persists longer than 24 hours.

Dosage & Administration

  • Benign gastric ulcer: 40 mg daily in the morning for 4 weeks, continued for further 4 weeks if not fully healed
  • Gastro-esophageal reflux disease: 20-40 mg daily in the morning for 4 weeks, continued for further 4 weeks if not fully healed; maintenance dose is 20 mg daily, which may be increased to 40 mg daily
  • Duodenal ulcer: 40 mg daily in the morning for 2 weeks, continued for further 2 weeks if not fully healed
  • Duodenal ulcer associated with Helicobacter pylori: Pantoprazole is recommended at a dose of 40 mg twice daily in association with antimicrobial agents for one week
  • Prophylaxis of NSAID-associated gastric or duodenal ulcer: 20 mg daily for those who require long-term NSAID treatment
  • Zollinger-Ellison Syndrome: Initially 80 mg once daily adjusted according to response, daily doses above 80 mg given in 2 divided doses
  • IV Injection for various conditions

Interaction

No significant drug interactions observed in clinical studies

Contraindications

Pantoprazole is contraindicated in patients with known hypersensitivity to any of the components of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Abdominal pain
  • Flatulence
  • Rash
  • Insomnia
  • Hyperglycemia

Pregnancy & Lactation

US FDA Pregnancy Category B, no adequate and well-controlled studies in pregnant woman. Drug should be used during pregnancy only if clearly needed. Pantoprazole has been shown to be excreted in human milk.

Precautions & Warnings

  • Tablet should not be split, chewed or crushed
  • Long-term therapy may lead to malabsorption of Vitamin B12
  • May increase risk of osteoporosis related disorders

Overdose Effects

No known symptoms of overdosage in humans. Since Panton-AX is highly protein bound, it is not readily dialyzable.

Therapeutic Class

Proton Pump Inhibitor

Reconstitution

IV injection should be given as a slow intravenous injection. The solution for IV injection is obtained by adding 10 ml 0.9% Sodium Chloride Injection to the vial containing powder. After reconstitution the injection should be given slowly over a period of at least 2 to 5 minutes. IV infusion should be given as an intravenous infusion over a period of approximately 15 minutes.

Storage Conditions

Keep in a dry place, away from light and heat. Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C16H15F2N3O4S
  • Chemical Structure: Pantoprazole Sodium

Common Questions about Panton-AX 40 mg Tablet

  • What is Panton-AX 40 mg Tablet? It suppresses the final step in gastric acid production. It is used to treat various conditions
  • How long do I need to use Panton-AX 40 mg Tablet before I see improvement in my condition? Till you see an improvement in your health conditions
  • At what frequency do I need to use Panton-AX 40 mg Tablet? In the dosage as prescribed by the doctor
  • Should I use Panton-AX 40 mg Tablet empty stomach, before food or after food? Prior to the meal, approximately 30 minutes before it
  • What are the instructions for the storage and disposal of Panton-AX 40 mg Tablet? Kept in a cool dry place in its original packaging
  • What are the effects of Panton-AX 40 mg Tablet on older adults? May increase the risk for bone fractures, especially with longer use, higher doses in older adults
  • How long does it take for Panton-AX 40 mg Tablet to work? 2 to 3 days to start feeling better, may take up to 4 weeks to work properly
  • Is Panton-AX 40 mg Tablet safe? Relatively safe. It is advised to consult the doctor before consuming
  • Does Panton-AX 40 mg Tablet cause weight gain? In rare cases, can cause weight gain
  • What are the side effects of Panton-AX 40 mg Tablet? Headache, diarrhea, constipation, and allergic reaction
  • Can I take Panton-AX 40 mg Tablet if I am pregnant or breastfeeding? It's advised not to take unless prescribed by the doctor
  • What should I do if I miss a dose of Panton-AX 40 mg Tablet? Take it as soon as you remember, if close to the time for your next dose, skip the missed dose and take your next dose at the regular time

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