Melizin 50 mg (Tablet)

Indications

• Nausea
• Vomiting
• Motion sickness
• Vertigo

Pharmacology

• Antiemetic
• Anticholinergic
• Antihistaminic
• Reduces sensitivity of labyrinthine apparatus
• Action mediated through nerve pathways to vomiting center

Dosage & Administration

• Adult dosage: 25-50 mg once daily
• Motion sickness: Initial dose of 25-50 mg, repeat every 24 hours if needed
• Vertigo: 25-100 mg daily in divided doses
• Children dosage: Age 6-12 years, 12.5 mg once daily; Age 2-6 years, 6.25 mg once daily
• Use in children: Determined by physician
• Elderly use: Sensitivity to anticholinergic effects

Interaction

• Increases toxicity with CNS depressants, neuroleptics, anticholinergic
• Potentiates drowsiness with alcohol, sedatives, tranquilizers

Contraindications

• Hypersensitivity to Meclizine or excipeints

Side Effects

• Drowsiness
• Dry mouth
• Blurred vision (rare)

Pregnancy & Lactation

• No risk of birth defects or abnormalities during pregnancy
• Excretes into milk, causes no harm in nursing babies

Precautions & Warnings

• Caution in patients with asthma, bronchitis, emphysema, enlarged prostate, glaucoma, urinary tract blockage

Overdose Effects

• Symptoms: Extreme excitability, seizures, hallucinations
• Treatment: Supportive and symptomatic treatment, consider dialysis

Therapeutic Class

• Anti-emetic drugs

Storage Conditions

• Store in a cool & dry place, away from children

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