Megestol 200 mg/5 ml (Oral Suspension)

100 ml bottle: ৳ 500.00

Medicine Details

Category Details
Generic Megestrol acetate
Company Ziska pharmaceuticals ltd
Also available as

Indications

  • Palliative treatment of advanced carcinoma of the breast or endometrium
  • Treatment of anorexia, cachexia, or unexplained weight loss in patients with AIDS & cancer

Pharmacology

  • Synthetic, antineoplastic, progestational drug
  • Mechanism of action against endometrial carcinoma
  • Antineoplastic action on carcinoma of the breast
  • Estrogen secretion inhibition
  • Plasma concentration
  • Plasma half-life
  • Excretion in urine and faeces

Dosage & Administration

  • Tablet dosage for breast cancer
  • Tablet dosage for endometrial carcinoma
  • Recommended period for determining efficacy
  • Oral suspension dosage

Interactions

  • Interactions with concomitant medications
  • Fluid retention with estrogens and progestogens

Contraindications

  • Hypersensitivity to Megestrol Acetate or any component
  • Known or suspected pregnancy

Side Effects

  • Weight gain
  • Thromboembolic phenomena
  • Glucocorticoid effects
  • Nausea
  • Dyspnea
  • Tumor flare
  • Hyperglycemia
  • Glucose intolerance
  • Alopecia
  • Hypertension
  • Carpal tunnel syndrome
  • Mood changes
  • Hot flashes
  • Malaise
  • Asthenia
  • Lethargy
  • Sweating
  • Rash

Pregnancy & Lactation

  • Pregnancy category
  • Excretion in mother's milk
  • Adverse effects on the newborn
  • Discontinuation of nursing

Precautions & Warnings

  • Close surveillance for patients with recurrent or metastatic cancer
  • Caution in patients with a history of thromboembolic disease
  • Exacerbation of preexisting diabetes

Use in Special Populations

  • Pediatric use
  • Geriatric use

Overdose Effects

  • No serious unexpected side effects reported

Storage Conditions

  • Temperature and humidity conditions
  • Protection from light and moisture
  • Keep out of reach of children

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