Betanem 1 gm/vial (IV Injection or Infusion)

1 gm vial: ৳ 1,250.00

Medicine Details

Category Details
Generic Meropenem trihydrate
Company Kemiko pharmaceuticals ltd
Also available as
Betanem 500 mg injection

Indications

  • Pneumonia and Nosocomial Pneumonia
  • Urinary Tract Infections
  • Intra-abdominal Infections
  • Gynaecological Infections
  • Skin and Skin Structure Infections
  • Meningitis
  • Septicaemia
  • Pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

  • Bactericidal action
  • Interference with bacterial cell wall synthesis
  • Penetration of bacterial cell walls
  • Stability to all serine beta-lactamases
  • Affinity for Penicillin Binding Proteins (PBPs)
  • Activity against Gram-positive and Gram-negative bacteria
  • Activity against aerobic and anaerobic bacteria

Dosage

  • Recommended daily dosage for adults and children
  • Dosage adjustments based on type and severity of infection
  • Intravenous administration
  • Intravenous infusion
  • Intravenous bolus
  • Dosage for different types of infections

Administration

  • Intravenous Infusion over approximately 15-30 minutes
  • Intravenous bolus over approximately 3-5 minutes

Interaction

  • Interaction with Probenecid
  • Inhibition of renal excretion
  • Effect on plasma concentration
  • Reduction of serum valproic acid levels

Contraindications

  • Hypersensitivity to the product

Side Effects

  • Inflammation
  • Thrombophlebitis
  • Pain at the site of injection
  • Skin reactions like rash, pruritus, urticaria
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

Pregnancy & Lactation

  • Pregnancy Category B
  • Caution during pregnancy
  • Excretion in human milk
  • Caution when administered to a nursing woman

Precautions & Warnings

  • Allergic reaction
  • Discontinuation in case of allergic reaction
  • Monitoring of transaminase and bilirubin levels in patients with hepatic disease

Use in Special Populations

  • Dosage reduction in patients with renal impairment
  • No dosage adjustments in patients with hepatic impairment
  • Use in elderly patients
  • Efficacy and tolerability in infants under 3 months

Overdose Effects

  • Accidental overdose
  • Symptomatic treatment
  • Rapid renal elimination in normal individuals
  • Haemodialysis for removal in subjects with renal impairment

Therapeutic Class

  • Other beta-lactam Antibiotics

Reconstitution

  • Preparation of solution for intravenous bolus Administration
  • Preparation of solution for intravenous infusion administration
  • Compatibility with various infusion fluids
  • Potency maintenance for up to 3 hours at up to 25°C or 13 hours at up to 5°C

Storage Conditions

  • Storage in a cool, dry place (below 30°C)
  • Protection from light and moisture
  • Keep out of the reach of children

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