Betanem 500 mg/vial (IV Injection or Infusion)

500 mg vial: ৳ 700.00

Medicine Details

Category Details
Generic Meropenem trihydrate
Company Kemiko pharmaceuticals ltd
Also available as
Betanem 1 gm injection

Indications

  • Pneumonia and Nosocomial Pneumonia
  • Urinary Tract Infections
  • Intra-abdominal Infections
  • Gynaecological Infections
  • Skin and Skin Structure Infections
  • Meningitis
  • Septicaemia
  • Pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

Bactericidal action by interfering with bacterial cell wall synthesis. Potent bactericidal activity against a broad spectrum of bacteria.

Dosage

  • Adults:
    • 500 mg to 1 gm by intravenous administration every 8 hours
    • 1 g IV every 8 hours for nosocomial pneumonia, peritonitis, presumed infections in neutropenic patients, septicaemia
    • 2 gm IV every 8 hours for meningitis
    • Upto 2 gm every 8 hours for cystic fibrosis
  • Children:
    • 10 to 40 mg/kg intravenously every 8 hours depending on type and severity of infection
    • 20 mg/kg every 8 hours for intra-abdominal infections
    • 25-40 mg/kg every 8 hours for cystic fibrosis (4-18 years)
    • 40 mg/kg IV every 8 hours for meningitis
    • 20 mg/kg every 8 hours for febrile neutropenia

Administration

Intravenous Infusion over approximately 15-30 minutes or as intravenous bolus (5 to 20 ml) over approximately 3-5 minutes

Interaction

Probenecid competes with Betanem for active tubular secretion, may reduce serum valproic acid levels

Contraindications

Hypersensitivity to the product

Side Effects

  • Inflammation at injection site
  • Thrombophlebitis
  • Pain at the site of injection
  • Skin reactions like rash, pruritus, urticaria
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

Pregnancy & Lactation

Pregnancy Category B. Caution advised during lactation

Precautions & Warnings

Discontinue in case of allergic reaction. Use with caution in hepatic disease patients

Special Populations

  • Dosage adjustment in renal impairment
  • No dosage adjustments necessary in hepatic impairment
  • No dosage adjustments necessary in elderly patients
  • Efficacy and tolerability in infants under 3 months not established

Overdose Effects

Accidental overdose could occur, treatment should be symptomatic

Therapeutic Class

Other beta-lactam Antibiotics

Reconstitution

Intravenous bolus & infusion administration methods and compatible infusion fluids provided

Storage Conditions

Store below 30°C, away from light & moisture, keep out of the reach of children

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