Menem 1 gm/vial (IV Injection or Infusion)

1 gm vial: ৳ 1,300.00

Medicine Details

Category Details
Generic Meropenem trihydrate
Company Astra biopharmaceuticals ltd
Also available as
Menem 500 mg injection

Indications

  • Pneumonia and Nosocomial Pneumonia
  • Urinary Tract Infections
  • Intra-abdominal Infections
  • Gynaecological Infections
  • Skin and Skin Structure Infections
  • Meningitis
  • Septicaemia
  • Pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

Bactericidal action by interfering with bacterial cell wall synthesis, Potent bactericidal activity against a broad spectrum of bacteria

Dosage

  • Adults:
    • Usual dose: 500 mg to 1 gm by intravenous administration every 8 hours
    • Specific dosages for different infections
  • Children:
    • Dosage based on age and severity of infection
    • Specific dosages for different infections
    • Caution for children over 50 kg weight to use adult dosage

Administration

Intravenous Infusion over approximately 15-30 minutes or as intravenous bolus over 3-5 minutes

Interaction

Probenecid competes with Menem for active tubular secretion

Contraindications

Hypersensitivity to this product

Side Effects

  • Inflammation
  • Thrombophlebitis
  • Pain at the site of injection
  • Skin reactions like rash, pruritus, urticaria
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

Pregnancy & Lactation

Pregnancy Category B, Caution for nursing women

Precautions & Warnings

  • Discontinue if allergic reaction occurs
  • Careful monitoring in patients with hepatic disease

Use in Special Populations

  • Renal impairment: Dosage reduction
  • Hepatic impairment: No dosage adjustments necessary
  • Elderly: No dosage adjustments necessary unless creatinine clearance is less than 51 ml/min
  • Children: Efficacy and tolerability in infants under 3 months not established

Overdose Effects

Symptomatic treatment, Hemodialysis for renal impaired patients

Therapeutic Class

Other beta-lactam Antibiotics

Reconstitution

  • Intravenous bolus Administration: Reconstitute Menem with sterile water for injection
  • Intravenous infusion administration: Mix with compatible infusion fluids, use freshly reconstituted solution

Storage Conditions

Store in a cool, dry place (below 30°C), away from light & moisture, Keep out of the reach of children

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