Meropen 250 mg/vial (IV Injection or Infusion)

250 mg vial: ৳ 400.00

Medicine Details

Category Details
Generic Meropenem trihydrate
Company Renata limited
Also available as
Meropen 500 mg injection Meropen 1 gm injection

Indications

  • Pneumonia and Nosocomial Pneumonia
  • Urinary Tract Infections
  • Intra-abdominal Infections
  • Gynaecological Infections
  • Skin and Skin Structure Infections
  • Meningitis
  • Septicaemia
  • Pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

  • Bactericidal action
  • Interferes with bacterial cell wall synthesis
  • Potent bactericidal activity
  • Works against a broad spectrum of bacteria

Dosage

  • Dosage depends on type and severity of infection
  • Different dosages for adults and children
  • Dosage administration every 8 hours
  • Intravenous administration

Administration

  • Administered by intravenous infusion
  • Infusion over approximately 15-30 minutes
  • Intravenous bolus administration

Interaction

  • Interaction with probenecid
  • Competition for active tubular secretion
  • Inhibition of renal excretion

Contraindications

  • Hypersensitivity to the product

Side Effects

  • Inflammation
  • Thrombophlebitis
  • Pain at injection site
  • Skin reactions
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

Pregnancy & Lactation

  • Pregnancy Category B
  • Caution during breastfeeding

Precautions & Warnings

  • Allergic reaction precautions
  • Monitoring of hepatic disease patients

Use in Special Populations

  • Dosage for patients with renal impairment
  • No dosage adjustments for hepatic impairment
  • Use in elderly patients
  • Efficacy and tolerability in infants under 3 months not established

Overdose Effects

  • Accidental overdose
  • Symptomatic treatment
  • Rapid renal elimination in normal individuals
  • Haemodialysis for subjects with renal impairment

Therapeutic Class

  • Other beta-lactam Antibiotics

Reconstitution

  • Preparation of intravenous bolus Administration
  • Preparation of intravenous infusion administration
  • Compatibility with various infusion fluids
  • Recommendation for use of freshly reconstituted solution
  • Recommended storage conditions for reconstituted solution

Storage Conditions

  • Store in a cool, dry place
  • Store below 30°C
  • Keep away from light and moisture
  • Keep out of the reach of children

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