Oropem 1 gm/vial (IV Injection or Infusion)

1 gm vial: ৳ 1,300.00

Medicine Details

Category Details
Generic Meropenem trihydrate
Company Euro pharma ltd

Title and Categories

  • Oropem Antibiotic
  • Pharmaceutical Product
  • Therapeutic Class
  • Parenteral Use

Indications

  • Pneumonia and Nosocomial Pneumonia
  • Urinary Tract Infections
  • Intra-abdominal Infections
  • Gynaecological Infections
  • Skin and Skin Structure Infections
  • Meningitis
  • Septicaemia
  • Pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

  • Carbapenem Antibiotic
  • Bactericidal Action
  • Interferes with Bacterial Cell Wall Synthesis
  • Potent Bactericidal Activity against Gram-positive and Gram-negative Bacteria

Dosage

  • Dosage varies for Adults and Children
  • Intravenous Administration
  • Dosage based on type, severity of infection and patient's condition
  • Dosage for specific infections (Pneumonia, Urinary Tract Infections, Gynaecological Infections, Nosocomial Pneumonias, Intra-abdominal Infections, Cystic Fibrosis, Meningitis)

Administration

  • Intravenous Infusion over approximately 15-30 minutes
  • Intravenous Bolus over approximately 3-5 minutes

Interaction

  • Interaction with Probenecid
  • Competes for active tubular secretion
  • Inhibition of renal excretion
  • Reduction in serum valproic acid levels

Contraindications

  • Hypersensitivity to the product

Side Effects

  • Inflammation at injection site
  • Thrombophlebitis
  • Skin reactions like rash, pruritus, urticaria
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

Pregnancy & Lactation

  • Pregnancy Category B
  • Caution during lactation

Precautions & Warnings

  • Allergic reaction management
  • Careful monitoring in patients with hepatic disease

Use in Special Populations

  • Dosage adjustments in Renal Impairment
  • No adjustments for Hepatic Impairment
  • Monitoring in Elderly patients
  • Efficacy and tolerability in children under 3 months not established

Overdose Effects

  • Symptomatic treatment for accidental overdose
  • Rapid elimination in normal individuals
  • Haemodialysis in subjects with renal impairment

Reconstitution

  • Intravenous Bolus and Infusion preparation
  • Shaking to obtain clear and colorless solution
  • Compatibility with various infusion fluids

Storage Conditions

  • Store in a cool, dry place
  • Below 30°C
  • Protection from light & moisture
  • Keep out of the reach of children

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