Centomin 500 mg (Tablet)

Unit Price: ৳ 4.00 (10 x 10: ৳ 400.00)
Strip Price: ৳ 40.00

Medicine Details

Category Details
Generic Metformin hydrochloride
Company Centeon pharma ltd
Also available as
Centomin 850 mg tablet

Indications

  • Treatment of type 2 diabetes mellitus
  • Usage in adults and children from 10 years of age and adolescents
  • Reduction of diabetic complications in overweight patients

Pharmacology

  • Classified as a biguanide type oral antihyperglycemic drug
  • Lowers basal and postprandial plasma glucose levels
  • Decreases hepatic glucose production
  • Improves insulin sensitivity

Dosage & Administration

  • Available in immediate release and extended release tablets
  • Individualized dosage based on effectiveness and tolerance
  • Usual starting dose for adults and children
  • Instructions for renal impaired patients

Interaction

  • No information available about the interaction with Furosemide
  • Enhancement of absorption with Nifedipine
  • Potential interaction with cationic drugs
  • Effects on drugs that tend to produce hyperglycemia

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Acute metabolic acidosis and severe renal failure
  • Conditions with potential to alter renal function
  • Conditions causing tissue hypoxia

Side Effects

  • Hemolytic anemia
  • Lactic acidosis
  • Taste disturbance
  • Gastrointestinal disorders
  • Liver function test abnormalities
  • Skin reactions

Pregnancy & Lactation

  • Impact of uncontrolled diabetes during pregnancy
  • Excretion into human breast milk
  • Recommendations for breastfeeding during treatment

Precautions & Warnings

  • Substantial excretion by the kidney
  • Lowering of vitamin B12 level
  • Increased risk of hypoglycemia in combination with insulin
  • Specific advisories for surgical procedures

Use in Special Populations

  • Dosage adjustments for elderly subjects
  • Diagnosis confirmation before treatment in children
  • Regular assessment of renal function

Overdose Effects

  • Absence of hypoglycemia at high doses
  • Occurrence of lactic acidosis
  • Recommended treatment via hemodialysis

Therapeutic Class

  • Belongs to the class of biguanides

Storage Conditions

  • Keep below 30°C temperature
  • Protection from light and moisture
  • Keep out of reach of children

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