Centomin 500 mg (Tablet)
Unit Price: ৳ 4.00 (10 x 10: ৳ 400.00)
Strip Price: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Centeon pharma ltd |
| Also available as |
Indications
- Treatment of type 2 diabetes mellitus
- Usage in adults and children from 10 years of age and adolescents
- Reduction of diabetic complications in overweight patients
Pharmacology
- Classified as a biguanide type oral antihyperglycemic drug
- Lowers basal and postprandial plasma glucose levels
- Decreases hepatic glucose production
- Improves insulin sensitivity
Dosage & Administration
- Available in immediate release and extended release tablets
- Individualized dosage based on effectiveness and tolerance
- Usual starting dose for adults and children
- Instructions for renal impaired patients
Interaction
- No information available about the interaction with Furosemide
- Enhancement of absorption with Nifedipine
- Potential interaction with cationic drugs
- Effects on drugs that tend to produce hyperglycemia
Contraindications
- Hypersensitivity to the active substance or excipients
- Acute metabolic acidosis and severe renal failure
- Conditions with potential to alter renal function
- Conditions causing tissue hypoxia
Side Effects
- Hemolytic anemia
- Lactic acidosis
- Taste disturbance
- Gastrointestinal disorders
- Liver function test abnormalities
- Skin reactions
Pregnancy & Lactation
- Impact of uncontrolled diabetes during pregnancy
- Excretion into human breast milk
- Recommendations for breastfeeding during treatment
Precautions & Warnings
- Substantial excretion by the kidney
- Lowering of vitamin B12 level
- Increased risk of hypoglycemia in combination with insulin
- Specific advisories for surgical procedures
Use in Special Populations
- Dosage adjustments for elderly subjects
- Diagnosis confirmation before treatment in children
- Regular assessment of renal function
Overdose Effects
- Absence of hypoglycemia at high doses
- Occurrence of lactic acidosis
- Recommended treatment via hemodialysis
Therapeutic Class
- Belongs to the class of biguanides
Storage Conditions
- Keep below 30°C temperature
- Protection from light and moisture
- Keep out of reach of children