Metguard 500 mg (Tablet)

Unit Price: ৳ 3.00 (60's pack: ৳ 180.00)

Medicine Details

Category Details
Generic Metformin hydrochloride
Company Guardian healthcare ltd

Title

Metguard Diabetes Medication

Categories

  • Medicine
  • Diabetes Management
  • Pharmacology
  • Medical Supplies

Description

Metguard is an oral antihyperglycemic drug used for the treatment of type 2 diabetes mellitus. It helps in lowering both basal and postprandial plasma glucose and improves insulin sensitivity.

Color Options

  • White

Functions

  • Lowering Blood Glucose Levels
  • Improving Insulin Sensitivity
  • Managing Type 2 Diabetes Mellitus

Materials

  • Metformin Hydrochloride
  • Tablet Coating Material

Technical Specifications

  • Dosage Form: Immediate Release Tablet, Extended Release Tablet
  • Dosage Range: 500mg to 2550mg per day for adults, up to 2000mg per day for children
  • Storage Conditions: Below 30°C, protected from light and moisture

Design Elements

  • Round Tablet Shape
  • Coated for Ease of Swallowing

Usability Features

  • Individualized Dosage Based on Effectiveness and Tolerance
  • Swallow Whole - Do Not Crush, Cut, or Chew

Indications

  • Treatment of Type 2 Diabetes Mellitus
  • Reduction of Diabetic Complications
  • Monotherapy or Combination Therapy for Adults and Children from 10 Years of Age

Pharmacology

  • Lowers Basal and Postprandial Plasma Glucose
  • Improves Insulin Sensitivity
  • Different Mechanism of Action from Sulfonylureas

Interaction

  • No Chronic Co-administration Information with Furosemide
  • Enhancement of Nifedipine Absorption
  • Potential Interaction with Cationic Drugs that are Eliminated by Renal Tubular Secretion

Dosage & Administration

  • Individualized Dosage Based on Effectiveness and Tolerance
  • Dosage Increases in Increments of 500mg or 850mg
  • Dosage Adjustment for Renal Impaired Patients

Contraindications

  • Hypersensitivity to Active Substance or Excipients
  • Acute Metabolic Acidosis
  • Severe Renal Failure (GFR < 30 mL/min)

Side Effects

  • Hemolytic Anemia
  • Lactic Acidosis
  • Decrease of Vitamin B12 Absorption
  • Taste Disturbance
  • Gastrointestinal Disorders
  • Liver Function Test Abnormalities
  • Skin Reactions

Pregnancy & Lactation

  • Increased Risk of Congenital Abnormalities and Perinatal Mortality with Uncontrolled Diabetes During Pregnancy
  • Metformin Excretion into Breast Milk
  • No Adverse Effects on Breastfed Newborns/Infants Observed

Precautions & Warnings

  • Substantial Excretion by the Kidney
  • Lower Vitamin B12 Level
  • Increased Risk of Hypoglycemia with Insulin or Insulin Secretagogue Combination
  • Regular Monitoring of Renal Function Advised

Special Populations

  • Elderly - Adjusted Dosage Based on Renal Function
  • Pediatric - Confirmation of Type 2 Diabetes Mellitus Before Treatment Initiation
  • Regular Follow-up Recommended for Effects on Growth and Puberty

Overdose Effects

  • Lactic Acidosis Medical Emergency - Treat in Hospital
  • Hemodialysis for Removing Lactate and Metguard

Therapeutic Class

Biguanides

Storage Conditions

Below 30°C, Protected from Light & Moisture, Keep Out of Reach of Children

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