Dia M 850 mg (Tablet)
Unit Price: ৳ 2.50 (50's pack: ৳ 125.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Medimet pharmaceuticals ltd |
| Also available as |
Indications
- Type 2 diabetes mellitus treatment
- Adult use
- Pediatric use
- Reduction of diabetic complications
- First-line therapy after diet failure
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers basal and postprandial plasma glucose
- Mechanism different from sulfonylureas
- Improves insulin sensitivity
- Decreases hepatic glucose production
Dosage & Administration
- Individualized dosage
- Maximum recommended daily doses
- Immediate release tablet
- Extended release tablet
- Dosage for adults
- Dosage for children
- Dosage increments
- Renal impaired patient dosage
Interaction
- Interaction with Furosemide
- Interaction with Nifedipine
- Potential interaction with cationic drugs
- Effect on Cimetidine pharmacokinetics
- Drugs that produce hyperglycemia
Contraindications
- Hypersensitivity
- Acute metabolic acidosis
- Severe renal failure
- Conditions altering renal function
- Conditions causing tissue hypoxia
Side Effects
- Hemolytic anemia
- Lactic acidosis
- Decrease of vitamin B12 absorption
- Peripheral neuropathy
- Taste disturbance
- Gastrointestinal disorders
- Hepatic function test abnormalities
- Skin reactions
Pregnancy & Lactation
- Risk of congenital abnormalities
- Use of insulin during pregnancy
- Excretion into human breast milk
- No adverse effects observed in breastfed newborns/infants
Precautions & Warnings
- Excretion by the kidney
- Risk of Dia M accumulation and lactic acidosis
- Lowering of vitamin B12 level
- Increased risk of hypoglycemia
- Surgery and clinical investigations precautions
Use in Special Populations
- Elderly dosage adjustment
- Effect on growth and puberty
- Renal function assessment
- Caution in children aged 10-12 years
Overdose Effects
- Hypoglycemia
- Lactic acidosis
- Emergency treatment in hospital
- Hemodialysis for lactic acidosis
Therapeutic Class
- Biguanides
Storage Conditions
- Temperature below 30°C
- Protected from light & moisture
- Keep out of the reach of children