Sumin 500 mg (Tablet)
Unit Price: ৳ 2.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Orbit pharmaceuticals ltd |
Indications
- Treatment of type 2 diabetes mellitus
- Used in adults and children from 10 years of age
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers basal and postprandial plasma glucose
- Improves insulin sensitivity
Dosage & Administration
- Individualized dosage based on effectiveness and tolerance
- Dosage increases in increments
- Different dosages for immediate release and extended release tablets
Interaction
- No chronic interaction with Furosemide
- Enhances absorption of Nifedipine
- Potential interaction with cationic drugs and certain other medications
Contraindications
- Hypersensitivity to the active substance
- Acute metabolic acidosis
- Severe renal failure
- Acute conditions altering renal function
Side Effects
- Hemolytic anemia
- Lactic acidosis
- Decreased vitamin B12 absorption
- Peripheral neuropathy
- Taste disturbance
- Gastrointestinal disorders
- Liver function test abnormalities
- Skin reactions
Pregnancy & Lactation
- Increased risk of congenital abnormalities and perinatal mortality
- Excretion into human breast milk
- Breastfeeding not recommended during treatment
Precautions & Warnings
- Substantial excretion by the kidney
- Lowering of vitamin B12 level
- Increased risk of hypoglycemia
- Regular monitoring of renal function
- Special caution in elderly and pediatric population
Use in Special Populations
- Adjustment of metformin dosage in elderly subjects
- Careful follow-up on metformin effect in children
- Regular assessment of renal function
- Particular caution in children aged between 10 and 12 years
Overdose Effects
- Hypoglycemia not seen at high doses
- Lactic acidosis may occur
- Hemodialysis for treatment
Therapeutic Class
- Biguanides
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children