Sumin 500 mg (Tablet)

Unit Price: ৳ 2.00

Medicine Details

Category	Details
Generic	Metformin hydrochloride
Company	Orbit pharmaceuticals ltd

Indications

Treatment of type 2 diabetes mellitus
Used in adults and children from 10 years of age

Pharmacology

Biguanide type oral antihyperglycemic drug
Lowers basal and postprandial plasma glucose
Improves insulin sensitivity

Dosage & Administration

Individualized dosage based on effectiveness and tolerance
Dosage increases in increments
Different dosages for immediate release and extended release tablets

Interaction

No chronic interaction with Furosemide
Enhances absorption of Nifedipine
Potential interaction with cationic drugs and certain other medications

Contraindications

Hypersensitivity to the active substance
Acute metabolic acidosis
Severe renal failure
Acute conditions altering renal function

Side Effects

Hemolytic anemia
Lactic acidosis
Decreased vitamin B12 absorption
Peripheral neuropathy
Taste disturbance
Gastrointestinal disorders
Liver function test abnormalities
Skin reactions

Pregnancy & Lactation

Increased risk of congenital abnormalities and perinatal mortality
Excretion into human breast milk
Breastfeeding not recommended during treatment

Precautions & Warnings

Substantial excretion by the kidney
Lowering of vitamin B12 level
Increased risk of hypoglycemia
Regular monitoring of renal function
Special caution in elderly and pediatric population

Use in Special Populations

Adjustment of metformin dosage in elderly subjects
Careful follow-up on metformin effect in children
Regular assessment of renal function
Particular caution in children aged between 10 and 12 years

Overdose Effects

Hypoglycemia not seen at high doses
Lactic acidosis may occur
Hemodialysis for treatment

Therapeutic Class

Biguanides

Storage Conditions

Keep below 30°C temperature
Protected from light & moisture
Keep out of the reach of children

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