Metfo XR 1000 mg (Tablet (Extended Release))

Unit Price: ৳ 10.00 (6 x 5: ৳ 300.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Metformin hydrochloride
Company Pacific pharmaceuticals ltd
Also available as
Metfo 500 mg tablet Metfo 850 mg tablet Metfo xr 500 mg tablet Metfo xr 750 mg tablet

Indications

  • Treatment of type 2 diabetes mellitus
  • For overweight patients
  • Monotherapy or combination therapy
  • Reduction of diabetic complications
  • For adults and children 10 years and older

Pharmacology

  • Biguanide type oral antihyperglycemic drug
  • Lowers basal and postprandial plasma glucose
  • Improves insulin sensitivity
  • Decreases hepatic glucose production

Dosage & Administration

  • Individualized dosing
  • Dosage increments
  • Different dosages for immediate and extended release tablets
  • Maximum recommended daily doses
  • Special dosage for renal impaired patients

Interaction

  • Interactions with Furosemide and Nifedipine
  • Cationic drug interactions
  • Effects on Cimetidine pharmacokinetics
  • Drugs that may lead to loss of glycemic control

Contraindications

  • Hypersensitivity reactions
  • Acute metabolic acidosis
  • Severe renal failure
  • Conditions affecting renal function
  • Conditions causing tissue hypoxia

Side Effects

  • Hemolytic anemia
  • Lactic acidosis
  • Vitamin B12 absorption decrease
  • Gastrointestinal disturbances
  • Peripheral neuropathy

Pregnancy & Lactation

  • Risk during pregnancy
  • Excretion in breast milk
  • Recommendations for breastfeeding
  • Avoidance during pregnancy

Precautions & Warnings

  • Renal function monitoring
  • Vitamin B12 level monitoring
  • Risk of hypoglycemia
  • Dehydration precautions
  • Annual Vitamin B12 level estimation

Use in Special Populations

  • Dosage adjustments for elderly
  • Effects on growth and puberty
  • Cautions in children aged 10-12 years
  • Renal function assessments
  • Caution in conditions affecting renal function

Overdose Effects

  • No hypoglycemia at high doses
  • Lactic acidosis risk
  • Emergency treatment in hospital
  • Hemodialysis for removal

Therapeutic Class

  • Belongs to Biguanides drug class

Storage Conditions

  • Temperature below 30°C
  • Protected from light & moisture
  • Keep out of reach of children

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