Radimet 500 mg (Tablet)
Unit Price: ৳ 4.00 (6 x 10: ৳ 240.00)
Strip Price: ৳ 40.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Radiant pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of type 2 diabetes mellitus
- Management of type 2 diabetes in overweight patients
- Monotherapy for adults with type 2 diabetes
- Combination therapy for adults with type 2 diabetes
- Combination therapy for children and adolescents with type 2 diabetes
Pharmacology
- Classified as a biguanide type oral antihyperglycemic drug
- Lowers both basal and postprandial plasma glucose
- Decreases hepatic glucose production
- Decreases intestinal absorption of glucose
- Improves insulin sensitivity
- Increases peripheral glucose uptake and utilization
Dosage & Administration
- Individualized dosage based on effectiveness and tolerance
- Maximum recommended daily doses
- Different dosages for immediate release and extended release tablets
- Dosage adjustments for adults and children
- Special considerations for renal impaired patients
Interaction
- No information available for interaction with Furosemide
- Potential interaction with Nifedipine
- Potential interaction with cationic drugs
- Minimal effects on Cimetidine pharmacokinetics
- List of drugs that may affect glycemic control
Contraindications
- Hypersensitivity to the active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Acute conditions affecting renal function
- Acute or chronic diseases causing tissue hypoxia
Side Effects
- Hemolytic anemia
- Lactic acidosis
- Decreased vitamin B12 absorption
- Peripheral neuropathy
- Taste disturbance
- Gastrointestinal disorders
- Liver function test abnormalities
- Skin reactions
Pregnancy & Lactation
- Increased risk of congenital abnormalities and perinatal mortality
- Recommendation to use insulin during pregnancy
- Excretion into human breast milk
- Limited data available for breastfeeding
Precautions & Warnings
- Substantial excretion by the kidney
- Lowering of vitamin B12 level
- Increased risk of hypoglycemia
- Recommendation for regular monitoring of renal function
- Caution in dehydration, serious infections or trauma
Use in Special Populations
- Adjusted dosage for elderly subjects
- Confirmation of type 2 diabetes mellitus before treatment
- No effect on growth and puberty detected in controlled studies
- Caution recommended for children aged between 10 and 12 years
Overdose Effects
- No hypoglycemia observed with doses up to 85 gm
- Potential occurrence of lactic acidosis
Therapeutic Class
- Biguanides
Storage Conditions
- Temperature below 30°C
- Protected from light and moisture
- Keep out of the reach of children