Minirfor 500 mg (Tablet)
Unit Price: ৳ 4.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metformin hydrochloride |
| Company | Rephco pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of type 2 diabetes mellitus
- Management of type 2 diabetes in overweight patients
Pharmacology
- Biguanide type oral antihyperglycemic drug
- Lowers basal and postprandial plasma glucose
- Decreases hepatic glucose production
- Improves insulin sensitivity
Dosage & Administration
- Dosage individualized based on effectiveness and tolerance
- Maximum recommended daily doses
- Usual starting dose for adults and children
- Usual starting dose for Metformin XR
- Dosage adjustments for renal impaired patients
Interaction
- Interaction with Furosemide and Nifedipine
- Interaction with cationic drugs and Cimetidine
- Drugs that may lead to loss of glycemic control
Contraindications
- Hypersensitivity to active substance or excipients
- Acute metabolic acidosis
- Severe renal failure
- Acute conditions altering renal function
- Conditions causing tissue hypoxia
Side Effects
- Hemolytic anemia
- Lactic acidosis
- Decrease of vitamin B12 absorption
- Peripheral neuropathy
- Taste disturbance
- Gastrointestinal disorders
- Liver function test abnormalities
- Skin reactions
Pregnancy & Lactation
- Risks of uncontrolled diabetes during pregnancy
- Recommendation against using metformin during pregnancy
- Excretion into human breast milk
Precautions & Warnings
- Excretion by the kidney
- Decreased vitamin B12 level
- Increased risk of hypoglycemia
- Regular monitoring of renal function
- Caution in conditions causing dehydration or serious infections
Use in Special Populations
- Dosage adjustment for elderly subjects
- Confirmation of type 2 diabetes mellitus before treatment
- Effect on growth and puberty in children
- Renal function assessment
- Caution in patients with GFR<30 ml/min
Overdose Effects
- Lactic acidosis as a medical emergency
- Hemodialysis for removal of lactate and Metformin
Therapeutic Class
- Biguanides
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children