SB-Met XR 1000 mg (Tablet (Extended Release))

Unit Price: ৳ 8.00 (30's pack: ৳ 240.00)

Medicine Details

Product Title

  • SB-Met XR

Categories

  • Medicine
  • Diabetes Management
  • Antihyperglycemic Drug
  • Biguanide

Description

  • SB-Met XR is used in the management of type 2 diabetes mellitus, particularly in overweight patients when dietary management and exercise alone do not result in adequate glycemic control. It lowers both basal and postprandial plasma glucose.

Dosage Form

  • Immediate Release Tablet
  • Extended Release Tablet

Recommended Dosage for Adults

  • Starting dose of 500 mg twice a day or 850 mg once a day, given with meals
  • Maximum daily dose of 2000 mg per day, given in divided doses
  • Dosage increases should be made in increments of 500 mg weekly or 850 mg every 2 weeks

Recommended Dosage for Children

  • Starting dose of 500 mg twice a day, given with meals
  • Maximum dose of 2000 mg per day, given in divided doses

Renal Impaired Patient Dosage

  • Do not use in patients with eGFR below 30 mL/min/1.73 m^2

Interaction with Other Drugs

  • May interact with Furosemide, Nifedipine, Cationic drugs, Cimetidine, Thiazides, Corticosteroids, Phenothiazines, and more

Contraindications

  • Hypersensitivity to the active substance or to any of the excipients
  • Acute metabolic acidosis
  • Severe renal failure
  • Acute conditions altering renal function
  • Conditions causing tissue hypoxia

Side Effects

  • Hemolytic anemia
  • Lactic acidosis
  • Decrease of vitamin B12 absorption
  • Taste disturbance
  • Gastrointestinal disorders
  • Liver function test abnormalities
  • Skin reactions

Pregnancy & Lactation

  • Use insulin during pregnancy to reduce risk of malformations
  • Metformin excreted into human breast milk
  • Breastfeeding not recommended during treatment

Precautions & Warnings

  • Excreted by the kidney
  • Increases risk of hypoglycemia
  • Regular monitoring of renal function advised
  • Dose adjustment in elderly subjects
  • Regular assessment of renal function necessary

Special Populations

  • Elderly subjects
  • Pediatric population
  • Renal function monitoring

Overdose Effects

  • Hypoglycemia has not been seen with SB-Met XR doses up to 85 gm
  • Lactic acidosis is a medical emergency and must be treated in hospital

Therapeutic Class

  • Biguanides

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light & moisture
  • Keep out of the reach of children

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