Meth 10 mg (Tablet)
Unit Price: ৳ 12.00 (2 x 14: ৳ 336.00)
Strip Price: ৳ 168.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Methotrexate |
| Company | Drug international ltd |
| Also available as |
Title
- Methotrexate Injection
Categories
- Chemotherapeutic agent
- Immunosuppressant
- Antidote preparation
Description
- Inhibits dihydrofolic acid reductase
- Interferes with DNA synthesis
- Used in the treatment of neoplastic diseases
- Indicated for rheumatoid arthritis and psoriasis
- Weekly dosage regimen for rheumatoid arthritis and psoriasis
- Administration on an empty stomach
- Interaction with NSAIDs, salicylates, phenylbutazone, phenytoin, sulfonamides
- Contraindicated in alcoholism, liver disease, immunodeficiency syndromes, pregnancy, lactation, and pre-existing blood dyscrasias
- Side effects include ulcerative stomatitis, leukopenia, nausea, abdominal distress, and fatigue
- Pregnancy Category X
- Leucovorin indicated for overdose effects
Dimensions
- Standard pharmaceutical vial size
Color Options
- Clear
Functions
- Inhibits DNA synthesis
- Interferes with cellular replication
- Controls psoriatic process
Materials
- Active ingredient: Methotrexate
- Preservatives-free formulations
Technical Specifications
- Induction dose for acute lymphoblastic leukemia and maintenance dose
- Multiple dosing regimens for neoplastic diseases
- Dosing for breast cancer, head and neck cancer, mycosis fungoides
Design Elements
- Packaging suitable for medical use
Usability Features
- Weekly dosing for rheumatoid arthritis and psoriasis
Pharmacology
- Inhibition of dihydrofolic acid reductase
- Interference with DNA synthesis
- Impairment of malignant cell growth
Dosage
- Oral and intramuscular administration
- Dosage for neoplastic diseases, acute lymphoblastic leukemia, lymphoma, breast cancer, head and neck cancer, rheumatoid arthritis, juvenile rheumatoid arthritis, and psoriasis
- Instructions for different stages and types of neoplastic diseases
Administration
- Empty stomach administration
- Can be taken with meals to reduce gastrointestinal discomfort
- Avoidance of consumption with milk-rich products
Interaction
- Interactions with NSAIDs, salicylates, phenylbutazone, phenytoin, sulfonamides, penicillin, theophylline, probenecid, azathioprine, retinoids, cisplatin, mercaptopurine, tetracycline, chloramphenicol, nonabsorbable broad spectrum antibiotics, vitamin preparations containing folic acid, trimethoprim/sulfamethoxazole
Contraindications
- Alcoholism, liver disease, immunodeficiency syndromes, pre-existing blood dyscrasias, hypersensitivity to methotrexate, pregnancy, lactation
Side Effects
- Ulcerative stomatitis, leukopenia, nausea, abdominal distress, fatigue, fertility impairment, menstrual dysfunction
Pregnancy & Lactation
- Pregnancy Category X
- Contraindicated in nursing mothers
Precautions & Warnings
- Avoidance of Methotrexate formulations containing preservatives for specific therapies
- Close monitoring for toxic effects
- Appropriate corrective measures for adverse reactions
- Increased alertness for possible recurrence of toxicity
- Evaluation of liver function test abnormalities
Use in Special Populations
- Benefit-risk assessment for pediatric patients
- Close monitoring of elderly patients
Overdose Effects
- Leucovorin indicated for diminishing toxicity and counteracting effects
Therapeutic Class
- Antidote preparations, Immunosuppressant
Storage Conditions
- Temperature not exceeding 30°C
- Dry place
- Protection from light and moisture