Acaril 50 mg (Tablet)
Unit Price: ৳ 15.00 (30's pack: ৳ 450.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Acarbose |
| Company | The white horse pharmaceuticals ltd |
Indications
- Improves glycemic control in adults with type 2 diabetes mellitus
Pharmacology
- Inhibition of pancreatic alpha-amylase and membrane-bound intestinal alpha-glucosidase enzymes
- Results in delayed glucose absorption and lowering of postprandial hyperglycemia
- Additive effect to enhance glycemic control when used in combination with other medications
Dosage & Administration
- Starting dosage of 25 mg three times daily
- Gradual dose titration to minimize gastrointestinal side effects
- Adjustment of dosage at 4-8 week intervals based on postprandial glucose or glycosylated hemoglobin levels
Interaction
- Certain drugs tend to produce hyperglycemia and may lead to loss of blood glucose control
- Withdrawal of interacting drugs should be closely observed for hypoglycemia
Contraindications
- Hypersensitivity to the drug
- Diabetic ketoacidosis or cirrhosis
- Inflammatory bowel disease, colonic ulceration, partial intestinal obstruction
- Chronic intestinal diseases associated with digestion or absorption disorders
Side Effects
- Diarrhea
- Gas
- Upset stomach
- Constipation
- Stomach pain
Pregnancy & Lactation
- Pregnancy Category B
- Not to be used by nursing women
Precautions & Warnings
- Should not cause hypoglycemia when administered alone
- Oral glucose should be used instead of sucrose in the treatment of mild to moderate hypoglycemia
- Severe hypoglycemia may require intravenous glucose infusion or glucagon injection
Use in Special Populations
- Safety and effectiveness in pediatric patients not established
- No overall differences in safety and effectiveness in geriatric patients observed
Overdose Effects
- Transient increases in flatulence, diarrhea, and abdominal discomfort
- Patient should avoid carbohydrates for 4-6 hours in case of overdosage
Therapeutic Class
- Alpha-Glucosidase inhibitor
Storage Conditions
- Store below 25°C
- Protect from moisture