Uni-Medrol 80 mg/2 ml (Injection)
80 mg vial: ৳ 100.00 (2's pack: ৳ 200.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Methylprednisolone acetate |
| Company | Chemist laboratories ltd |
Indications
- Treatment of asthma
- Treatment of atopic dermatitis
- Treatment of contact dermatitis
- Treatment of bullous dermatitis herpetiformis
- Treatment of mycosis fungoides
- Treatment of pemphigus
- Treatment of severe erythema multiforme
- Treatment of adrenocortical insufficiency
- Treatment of hypercalcemia associated with cancer
- Treatment of nonsuppurative thyroiditis
- Treatment of ulcerative colitis
- Palliative management of leukemias and lymphomas
- Treatment of sympathetic ophthalmia
- Treatment of keratitis
- Treatment of allergic conjunctivitis
- Treatment of juvenile rheumatoid arthritis
- Treatment of ankylosing spondylitis
- Treatment of symptomatic sarcoidosis
- Treatment of aspiration pneumonitis
Pharmacology
- Binds to and activates intracellular glucocorticoid receptors
- Modifies transcription and protein synthesis
- Inhibits leukocyte infiltration
- Interferes with mediators of inflammatory response
- Suppresses humoral immune responses
- Involves phospholipase A2 inhibitory proteins
Dosage & Administration
- Intra-articular administration for rheumatoid and osteoarthritis
- Intra-articular administration for miscellaneous conditions
- Dermatological conditions dosage
- Systemic effect dosage
- Multiple sclerosis treatment dosage
Interaction
- Convulsions with concurrent use of cyclosporine
- Induction of hepatic enzymes
- Inhibition of metabolism by certain drugs
- Effect on the clearance of chronic high dose aspirin
- Effect on anticoagulant when given concurrently
Contraindications
- Intrathecal administration
- Systemic fungal infections
- Known hypersensitivity to the product
Side Effects
- Congestive heart failure
- Hypertension
- Sodium retention
- Muscle weakness
- Osteoporosis
- Peptic ulcer
- Abdominal distention
- Increased sweating
- Convulsion
- Vertigo
- Headache
- Menstrual irregularities
- Increased intraocular pressure
- Glaucoma
- Allergic or hypersensitivity reactions
- Urticaria
- Hyperpigmentation or hypopigmentation
Pregnancy & Lactation
- Pregnancy Category C
- Potential hazards to the mother and embryo or fetus
Precautions & Warnings
- Use cautiously in patients with ocular herpes simplex
- Use cautiously in patients with nonspecific ulcerative colitis
- Use cautiously in patients with renal insufficiency
- Use cautiously in patients with hypertension
- Use cautiously in patients with osteoporosis
- Use cautiously in patients with myasthenia gravis
Therapeutic Class
- Glucocorticoids
Storage Conditions
- Store between 20-25°C