Medrol 40 mg/ml (Injection)
40 mg vial: ৳ 75.25 (1 x 5: ৳ 376.25)
Medicine Details
| Category | Details |
|---|---|
| Generic | Methylprednisolone acetate |
| Company | Techno drugs ltd |
| Also available as |
Indications
- Asthma
- Atopic dermatitis
- Contact dermatitis
- Bullous dermatitis herpetiformis
- Mycosis fungoides
- Pemphigus
- Erythema multiforme
- Adrenocortical insufficiency
- Hypercalcemia
- Thyroiditis
- Ulcerative colitis
- Hematologic disorders
- Leukemias
- Lymphomas
- Sympathetic ophthalmia
- Keratitis
- Allergic conjunctivitis
- Juvenile rheumatoid arthritis
- Ankylosing spondylitis
- Sarcoidosis
- Aspiration pneumonitis
Pharmacology
Methylprednisolone binds to and activates intracellular glucocorticoid receptors, modifying transcription and protein synthesis to inhibit inflammatory responses
Dosage & Administration
- Intra-articular administration for rheumatoid and osteoarthritis
- Miscellaneous conditions (ganglion, tendinitis, epicondylitis)
- Dermatological conditions
- Systemic effect for adrenogenital syndrome
- Systemic effect for rheumatoid arthritis
- Systemic effect for dermatologic lesions
- Acute severe dermatitis
- Chronic contact dermatitis
- Seborrheic dermatitis
- Asthma
- Allergic rhinitis
- Multiple sclerosis
Interaction
Concurrent use with cyclosporine may cause convulsions, enzyme-inducing drugs may increase clearance, troleandomycin and ketoconazole may inhibit metabolism, interactions with chronic high dose aspirin and anticoagulants reported
Contraindications
- Intrathecal administration
- Systemic fungal infections
- Known hypersensitivity to the product and its constituents
Side Effects
- Congestive heart failure
- Hypertension
- Sodium retention
- Muscle weakness
- Osteoporosis
- Peptic ulcer
- Hemorrhage
- Abdominal distention
- Increased sweating
- Convulsion
- Vertigo
- Headache
- Menstrual irregularities
- Adrenocortical and pituitary unresponsiveness
- Increased intraocular pressure
- Glaucoma
- Allergic reactions
- Urticaria
- Hyperpigmentation
- Hypopigmentation
Pregnancy & Lactation
Pregnancy Category C, benefits weighed against potential hazards
Precautions & Warnings
- Ocular herpes simplex
- Nonspecific ulcerative colitis
- Renal insufficiency
- Hypertension
- Osteoporosis
- Myasthenia gravis
Therapeutic Class
Glucocorticoids
Storage Conditions
Store between 20-25° C