Methsolon 16 mg (Tablet)

Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00

Medicine Details

Category Details
Generic Methylprednisolone
Company Incepta pharmaceuticals ltd
Also available as
Methsolon 4 mg tablet

Title

Methsolon

Categories

  • Medicine
  • Pharmaceuticals
  • Healthcare

Description

Methsolon is a potent anti-inflammatory steroid. It has greater anti-inflammatory potency than Prednisolone, even less tendency than prednisolone to induce sodium and water retention. The relative potency of Methsolon to Hydrocortisone is at least four to one.

Indications

  • Primary or Secondary Adrenocortical Insufficiency
  • Congenital Adrenal Hyperplasia
  • Rheumatoid Arthritis
  • Juvenile Rheumatoid Arthritis
  • Systemic Lupus Erythematosus
  • Allergic Rhinitis
  • Nephrotic Syndrome
  • Ulcerative Colitis
  • Multiple Sclerosis

Pharmacology

  • Pharmacodynamic Properties: Potent anti-inflammatory agent with the capacity to profoundly inhibit the immune system. Influences various bodily systems.
  • Pharmacokinetic Properties: High absolute bioavailability, rapid absorption, widely distributed into tissues, metabolized in the liver, haemodializable

Dosage and Administration

  • Usual Range: 2-48 mg daily in divided doses
  • Anti-inflammatory or Immunosuppressive Initial Dosage: 4-48 mg per day, variable based on disease severity
  • Anti-inflammatory or Immunosuppressive Maintenance Dosage: Adjusted based on response, constant monitoring needed
  • Multiple Sclerosis Treatment: 160 mg for a week followed by 64 mg every other day for 1 month

Interaction

  • Inhibitors:
    • Erythromycin
    • Clarithromycin
    • Phenobarbital
    • Phenytoin
    • Rifampin
    • Ketoconazole
  • Potentiators:
    • Estrogens (e.g. Birth Control Pills)

Contraindications

Systemic fungal infections and known hypersensitivity to components

Side Effects

  • Fluid retention
  • Weight gain
  • High blood pressure
  • Potassium loss
  • Headache
  • Muscle weakness
  • Growth retardation in children
  • Psychic disturbances

Pregnancy and Lactation

  • Category: Pregnancy category C
  • Recommendation: Given only if potential benefit justifies potential risk to the fetus

Precautions and Warnings

  • Adrenocortical insufficiency may persist after discontinuation of therapy
  • Enhanced effect on patients with hypothyroidism and in those with cirrhosis
  • Cautious use in patients with ocular herpes simplex
  • Careful observation of infants' and children's growth and development

Overdose Effects

Rare instances of acute toxicity and/or death. Supportive and symptomatic treatment recommended.

Therapeutic Class

Glucocorticoids

Storage Conditions

Cool, dry place away from light, keep out of reach of children

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