Depodrol 4 mg (Tablet)
Unit Price: ৳ 5.00 (4 x 14: ৳ 280.00)
Strip Price: ৳ 70.00
Medicine Details
Category | Details |
---|---|
Generic | Methylprednisolone |
Company | Opsonin pharma ltd |
Also available as | Depodrol 2 mg tabletDepodrol 8 mg tabletDepodrol 16 mg tablet |
Title
- Depodrol 4 mg Tablet
Categories
- Anti-inflammatory
- Immunosuppressive
- Glucocorticoid
Description
- Potent anti-inflammatory steroid
- Greater anti-inflammatory potency than Prednisolone
- Less tendency to induce sodium and water retention
Pharmacology
- Potent anti-inflammatory agent
- Inhibits the immune system
- Activates glucocorticoid receptors
- Influences various body systems
- Rapidly absorbed
- High bioavailability
- Metabolized in the liver
Dosage & Administration
- Usual range of 2-48 mg daily
- Initial dosage varies based on disease severity
- Maintenance dosage determined by response
- Treatment of acute exacerbations of multiple sclerosis
- Alternate-day therapy guidelines
Interactions
- Inhibition/metabolism by erythromycin, clarithromycin, phenobarbital, phenytoin, rifampin, ketoconazole
- Increased effect with estrogens
- Interaction with cyclosporin and blood thinners
Contraindications
- Systemic fungal infections
- Known hypersensitivity to components
Side Effects
- Short courses usually well-tolerated
- Long-term high doses may produce serious side effects
- Side effects range from mild to serious irreversible damage
- Fluid retention, weight gain, high blood pressure, muscle weakness, growth retardation in children, etc.
Pregnancy & Lactation
- Pregnancy category C
- Use in nursing mothers not adequately evaluated
Precautions & Warnings
- Possible persistence of adrenocortical insufficiency after discontinuation
- Enhanced effect on patients with hypothyroidism and cirrhosis
- Cautious use in patients with ocular herpes simplex
- Careful observation of infants' and children's growth and development during prolonged therapy
Overdose Effects
- Rare reports of acute toxicity or death
- No specific antidote available
- Supportive and symptomatic treatment
- Monitoring of serum electrolytes
Therapeutic Class
- Glucocorticoids
Storage Conditions
- Store in a cool, dry place away from light
- Keep out of reach of children