Pretonix 40 mg (Tablet (Enteric Coated))

Unit Price: ৳ 5.75 (30's pack: ৳ 172.50)

Medicine Details

Category Details
Generic Pantoprazole sodium
Company Pharmadesh laboratories ltd
Also available as
Pretonix 20 mg tablet

Indications

  • Peptic ulcer diseases
  • Gastroesophageal reflux diseases
  • Ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs)
  • Eradication of Helicobacter pylori (in combination with antibiotics)
  • Zollinger-Ellison Syndrome

Pharmacology

Proton pump inhibitor that suppresses the final step in gastric acid production by covalently binding to the H+/K+ ATPase enzyme system at the surface of the gastric parietal cell.

Dosage & Administration

  • Benign gastric ulcer: 40 mg daily in the morning for 4 weeks, continued for further 4 weeks if not fully healed
  • Gastro-esophageal reflux disease: 20-40 mg daily in the morning for 4 weeks, maintenance dose is 20 mg daily
  • Duodenal ulcer: 40 mg daily in the morning for 2 weeks, continued for further 2 weeks if not fully healed
  • Duodenal ulcer associated with Helicobacter pylori: 40 mg twice daily in association with antimicrobial agents for one week
  • Prophylaxis of NSAID-associated gastric or duodenal ulcer: 20 mg daily for long-term NSAID treatment
  • Zollinger-Ellison Syndrome: Initially 80 mg once daily adjusted according to response
  • Duodenal ulcer and gastric ulcer IV Injection: 40 mg once daily for 7-10 days

Interaction

No significant drug interactions observed in clinical studies

Contraindications

Patients with known hypersensitivity to any of the components of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Abdominal pain
  • Flatulence
  • Rash
  • Insomnia
  • Hyperglycemia

Pregnancy & Lactation

US FDA Pregnancy Category B. Should be used during pregnancy only if clearly needed. Excreted in human milk, decision should be made whether to discontinue nursing or discontinue the drug.

Precautions & Warnings

  • Tablet should not be split, chewed, or crushed
  • Long-term therapy may lead to malabsorption of Vitamin B12 or increase the risk of osteoporosis related disorders

Overdose Effects

No known symptoms of overdosage in humans. Not readily dialyzable. Apart from symptomatic and supportive management, no specific therapy is recommended

Therapeutic Class

Proton Pump Inhibitor

Reconstitution

IV injection should be given as a slow intravenous injection. Solution for IV injection obtained by adding 10 ml 0.9% Sodium Chloride Injection to the vial containing powder.

Storage Conditions

Keep in a dry place, away from light and heat. Keep out of the reach of children.

Chemical Structure

  • Molecular Formula: C16H15F2N3O4S
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-859-pantoprazole-sodium-chemical-structure-cnfmhAVGwpLzfJYlfu9P.svg

Common Questions

  • What is Pretonix 40 mg Tablet?
  • How long do I need to use Pretonix 40 mg Tablet before I see improvement in my condition?
  • At what frequency do I need to use Pretonix 40 mg Tablet?
  • Should I use Pretonix 40 mg Tablet empty stomach, before food or after food?
  • What are the instructions for the storage and disposal of Pretonix 40 mg Tablet?
  • What are the effects of Pretonix 40 mg Tablet on older adults?
  • How long does it take for Pretonix 40 mg Tablet to work?
  • Is Pretonix 40 mg Tablet safe?
  • Does Pretonix 40 mg Tablet cause weight gain?
  • What are the side effects of Pretonix 40 mg Tablet?
  • Can I take Pretonix 40 mg Tablet if I am pregnant or breastfeeding?
  • What should I do if I miss a dose of Pretonix 40 mg Tablet?

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