Solupred 16 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Methylprednisolone |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Title
Solupred Medication
Categories
- Medication
- Pharmaceutical
Description
Potent anti-inflammatory steroid with greater potency than Prednisolone and less tendency to induce sodium and water retention. Used for various indications including endocrine disorders, rheumatic disorders, collagen diseases, dermatologic diseases, and more.
Color Options
- white
Function
Anti-inflammatory, Immunosuppressive
Active Ingredient
Methylprednisolone
Pharmacodynamic Properties
Potent anti-inflammatory agent with impact on immune, kidney, fluid & electrolyte balance, metabolism, muscle, cardiovascular, nervous, and endocrine systems.
Pharmacokinetic Properties
High oral bioavailability, rapid absorption, wide tissue distribution, metabolism in the liver, haemodialyzable.
Dosage Range
2-48 mg daily in divided doses
Usability
- Anti-inflammatory or Immunosuppressive Initial Dosage: 4-48 mg per day
- Anti-inflammatory or Immunosuppressive Maintenance Dosage: Dependent on disease entity and patient's response
- Treatment of Multiple Sclerosis: 160 mg daily for a week followed by 64 mg every other day for 1 month
Administration
- Oral
Interactions
- Inhibitors:
- Erythromycin
- Clarithromycin
- Phenobarbital
- Phenytoin
- Rifampin
- Ketoconazole
- Enhancers:
- Estrogens, including Birth Control Pills
- With Cyclosporin: Reduced metabolism
- With Blood Thinners: Effect may be increased or decreased
Contraindications
- Systemic fungal infections
- Known hypersensitivity to components
Side Effects
- Short-Term: Few, mild side effects
- Long-Term, High Doses: Predictable and potentially serious side effects including fluid retention, weight gain, high blood pressure, potassium loss, headache, and more
Pregnancy & Lactation
Category C; benefits should justify potential risks to the fetus; inadequate evaluation in nursing mothers
Precautions & Warnings
Cautious usage in patients with adrenocortical insufficiency, hypothyroidism, cirrhosis, ocular herpes simplex, hypoprothrombinemia, and in children
Overdose Effects
Rare reports of acute toxicity and/or death; no specific antidote available; monitoring of serum electrolytes recommended
Therapeutic Class
Glucocorticoids
Storage Conditions
Cool, dry place, away from light; keep out of reach of children
Dimensions
N/A
Technical Specifications
N/A
Design Elements
N/A
Materials
N/A
Usability Features
Alternate-day therapy for corticosteroid dosing; gradual tapering to minimize corticosteroid insufficiency symptoms