Bexipred 1% (Ophthalmic Suspension)

5 ml drop: ৳ 100.00

Medicine Details

Category Details
Generic Prednisolone acetate
Company Beximco pharmaceuticals ltd

Indications

  • Treatment of steroid-responsive inflammation of the palpebral and bulbar conjunctiva
  • Treatment of steroid-responsive inflammation of the cornea
  • Treatment of steroid-responsive inflammation of the anterior segment of the globe

Pharmacology

  • Prednisolone decreases inflammation by inhibiting migration of polymorphonuclear leukocytes
  • Prednisolone reverses increased capillary permeability
  • Prednisolone suppresses the immune system by reducing the activity and production of lymphocytes
  • Prednisolone suppresses the immune system by reducing the activity and production of eosinophils

Dosage & Administration

  • Adult dosage: Instill one drop into the conjunctival sac two to four times daily
  • Paediatric dosage: Safety and effectiveness in pediatric patients have not been established
  • Initial 24 to 48 hours may require increased dosing frequency if necessary
  • Care should be taken not to discontinue the therapy before completing the course

Interaction

  • No significant drug interactions reported

Contraindications

  • Contraindicated in viral diseases of the cornea
  • Contraindicated in viral diseases of the conjunctiva
  • Contraindicated in known hypersensitivity to any ingredients of the preparation
  • Contraindicated in known hypersensitivity to other corticosteroids

Side Effects

  • Elevation of intraocular pressure (IOP)
  • Possible development of glaucoma
  • Infrequent optic nerve damage
  • Posterior subcapsular cataract formation
  • Delayed wound healing
  • Fungal and viral infections of the cornea may develop with long-term applications

Pregnancy & Lactation

  • Pregnancy category C
  • Use during pregnancy only if clearly needed

Precautions & Warnings

  • Shake the bottle well before use
  • Prolonged use may result in damage to the optic nerve
  • Prolonged use may result in defects in vision
  • Routine monitoring of intraocular pressure if used for longer periods

Overdose Effects

  • A one-time accidental overdose generally will not cause acute problems
  • Long-term overdose may show general side effects
  • In accidental overdose, sufficient water should be taken to dilute the medication

Therapeutic Class

  • Glucocorticoids

Storage Conditions

  • Store in a cool, dry place
  • Protect from light
  • Keep out of the reach of children
  • Protect from freezing
  • Shake well before using

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