Propenta 20 mg (Tablet (Enteric Coated))
Medicine Details
Category | Details |
---|---|
Generic | Pantoprazole sodium |
Company | Marker pharma ltd |
Indications
- Peptic ulcer diseases
- Gastroesophageal reflux diseases
- Ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs)
- Eradication of Helicobacter pylori (in combination with antibiotics)
- Zollinger-Ellison Syndrome
Pharmacology
Proton pump inhibitor that suppresses the final step in gastric acid production by covalently binding to the H⁺/K⁺ ATPase enzyme system at the surface of the gastric parietal cell.
Dosage & Administration
- Benign gastric ulcer: 40 mg daily in the morning for 4 weeks
- Gastro-esophageal reflux disease: 20-40 mg daily in the morning for 4 weeks
- Duodenal ulcer: 40 mg daily in the morning for 2 weeks
- Duodenal ulcer associated with Helicobacter pylori: 40 mg twice daily in association with antimicrobial agents for one week
- Prophylaxis of NSAID-associated gastric or duodenal ulcer: 20 mg daily
- Zollinger-Ellison Syndrome: Initially 80 mg once daily
IV Injection Dosage
- Duodenal ulcer and gastric ulcer: 40 mg once daily for 7-10 days
- Gastroesophageal reflux disease associated with a history of erosive esophagitis: 40 mg once daily for 7-10 days
- Prevention of rebleeding in peptic ulcer: IV 80 mg followed by 8 mg/hour infusion for 72 hours
Interaction
No significant drug interactions observed in clinical studies
Contraindications
Contraindicated in patients with known hypersensitivity to any of the components of the formulation
Side Effects
- Headache
- Diarrhea
- Abdominal pain
- Flatulence
- Rash
- Insomnia
- Hyperglycemia
Pregnancy & Lactation
US FDA Pregnancy Category B. No adequate and well-controlled studies in pregnant women.
Precautions & Warnings
Tablet should not be split, chewed, or crushed. Long-term therapy may lead to malabsorption of cyanocobalamin or increase the risk of osteoporosis related disorders
Overdose Effects
No known symptoms of overdosage. Highly protein bound, not readily dialyzable.
Therapeutic Class
Proton Pump Inhibitor
Reconstitution
IV injection and infusion should be given as per the directions provided.
Storage Conditions
Keep in a dry place, away from light and heat. Keep out of the reach of children
Chemical Structure
- Molecular Formula: C₁₆H₁₅F₂N₃O₄S
- Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-859-pantoprazole-sodium-chemical-structure-cnfmhAVGwpLzfJYlfu9P.svg
Common Questions
- What is Propenta 20 mg Tablet?: A proton pump inhibitor used to treat various conditions related to gastric acid production
- How long do I need to use Propenta 20 mg Tablet before I see improvement in my condition?: Till improvement is observed
- At what frequency do I need to use Propenta 20 mg Tablet?: As prescribed by the doctor
- Should I use Propenta 20 mg Tablet empty stomach, before food or after food?: Before meal, approximately 30 minutes before
- Storage and disposal instructions: Keep in a cool dry place, and in its original packaging
- Effects of Propenta 20 mg Tablet on older adults: May increase risk for bone fractures, especially with longer use, higher doses
- How long does it take for Propenta 20 mg Tablet to work?: Start to feel better within 2 to 3 days, may take up to 4 weeks to work properly
- Is Propenta 20 mg Tablet safe?: Relatively safe, consult the doctor before consumption
- Does Propenta 20 mg Tablet cause weight gain?: In rare cases, may cause weight gain
- Side effects of Propenta 20 mg Tablet: Headache, diarrhea, constipation, allergic reaction
- Can I take Propenta 20 mg Tablet if I am pregnant or breastfeeding?: Not a serious issue for pregnant or breastfeeding individuals, consult doctor for guidance
- What to do if I miss a dose of Propenta 20 mg Tablet?: Take as soon as remembered, skip if close to next dose
Related Brands
- Protium 20 mg (Tablet (Enteric Coated)) - unimed-unihealth-pharmaceuticals-ltd
- Protium 40 mg (Tablet (Enteric Coated)) - unimed-unihealth-pharmaceuticals-ltd
- Protocid 20 mg (Tablet (Enteric Coated)) - acme-laboratories-ltd
- Protocid 40 mg (Tablet (Enteric Coated)) - acme-laboratories-ltd
- Protocid 40 mg/vial (IV Injection) - acme-laboratories-ltd